M. Elizabeth Ross, M.D., Ph.D., is Head of the Laboratory of Neurogenetics and Development. The research in her laboratory centers on discovery of gene mutations associated with brain malformations and investigation of how these genes direct the construction of brain. Three major projects encompass: 1) neural tube formation, 2) cell cycle regulation and its role in cellular patterning of brain, and 3) regulation of neuronal migration to establish brain architecture. These three areas of study, all NIH funded, are approached from both basic science and clinical genetic perspectives.