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The Englander Institute for Precision Medicine at Weill Cornell Medicine is a translational research hub to promote molecular diagnostics and therapeutics.  Physician-scientists utilize the most advanced genomic sequencing technologies and novel computational algorithms to identify the genetic alterations that give rise to and drive each patient’s illness.   

The Englander Institute for Precision Medicine in New York City is an outstanding place to begin or grow your career. The Institute is located on the Upper East Side of Manhattan, along the East River.  We offer a highly competitive compensation package including excellent benefits.  Be sure to check out our featured spotlights here for employee profiles!

Academic

Research Pathology Fellowship in Precision Medicine

Position Summary:

The Englander Institute for Precision Medicine and the Department of Pathology and Laboratory Medicine at Weill Cornell Medicine offer a two-year Research Pathology Fellowship in Precision Medicine. With a major exposure to a comprehensive translational research component, this program will focus on the application of next-generation sequencing platforms to identify and validate novel alterations in an array of tumor types.

 

The goal of this Research Pathology Fellowship program is to gain expertise in the application of state-of-the-art sequencing technologies, familiarize with novel tools to analyze next-generation sequencing data, and to become leaders in the field of Precision Medicine. The Research Pathology Fellow will act as a bridge between pathologists, oncologists, surgeons, computational biologists and basic scientists, in order to use next-generation sequencing of tumor genomes and pre-clinical models in high impact research studies.

 

Responsibilities:

  • To review histopathology of research projects.
  • To familiarize with operation of next-generation sequencing platforms.
  • To learn about the data processing pipeline and bioinformatics aspects of next-generation sequencing. To be involved in the development and validation of research assays.
  • To participate in research pathology-related activities of next-generation biobanking including our pan-cancer Rapid Autopsy program.
  • To develop skills in sequencing data interpretation with computational scientists and bioinformaticians.
  • Salaries are commensurate with the level of training.

 

Qualifications:

Pathologists and pathology trainees will be considered. Prior experience in molecular biology/molecular pathology is encouraged.

 

Applications:

Applications: Please send Curriculum vitae, personal statement and two letters of recommendation to EIPMadmin@med.cornell.edu

Postdoctoral Fellow, Computational Biology

Position Summary:

The Englander Institute for Precision Medicine at Weill Cornell Medicine is seeking a highly motivated Postdoctoral fellow or Associate Research Scientist with strong expertise in bioinformatics to lead genetic analysis in human disease studies. The candidate will apply state-of-the-art computational methods to analyze large-scale sequencing data, including whole genome sequencing, interpret genetic variants, and identify novel human disease genes. The candidate will lead one or two of the major human genetics projects in the lab, focused on the following disease areas: cardiovascular, metabolic disease, neurodegenerative disorders, or cancer.

 

Responsibilities:

  • Lead bioinformatics projects to translate NGS data, as well as public and internal genomic, phenotype, and clinical/EMR datasets, to novel discoveries on a path to clinical utility.
  • Publish and present novel findings in academic journals and conferences.
  • D. with a background in cancer biology, bioinformatics or computational biology, or related fields.
  • For bioinformatics postdoctoral and research analyst positions, experience in statistical and programming languages (e.g., R, Python, Perl), experience in computational biology applications (e.g. bwa, samtools, GATK, etc.), and next-generation sequencing are required. The position offers opportunities for close collaboration with the world-class bioinformatics team at the Englander Institute for Precision Medicine.
  • High proficiency of Unix/Linux systems and code versioning tools.
  • Experience with code development, optimization, automation, and testing, using common version control solutions e.g. git.
  • Basic knowledge of molecular biology and genomics.
  • Knowledge of containerization platforms (e.g. Docker, Singularity).
  • Evidence of productivity from publications originating from Ph.D. or postdoctoral work.
  • The position requires the ability to work with a heterogenous group of basic scientists, molecular biologists, physician scientists, computational biologist, data scientists, lab technicians, medical and graduate students. Hence, it requires excellent verbal and written communication skills.
  • Excellent organizational skills, self-motivation, and creativity.

 

Qualifications:

  • PhD in Bioinformatics, Biomedical Informatics, Computational Biology, Genomics, or a related discipline requiring strong computational and analytical skills supplemented with biology background
  • Extensive knowledge of using high-performance computing clusters, including common scheduling systems (e.g. OGE, slurm, etc.)
  • Experience working with cloud computing infrastructures will be a plus, especially on Amazon AWS
  • Knowledge of workflow languages, e.g. CWL, Nextflow or equivalent is a plus.
  • Knowledge of agile software development preferred.
  • Well-versed in the art of effective communication on interdisciplinary teams (scientists, programmers, and clinicians), especially graphical communication about high-complexity datasets to scientific audiences from different backgrounds.
  • High self-motivation, great ability to work in both multiple-task and independent fashions.

 

Applications:

Motivated to pursue postdoctoral training required for a future independent academic career. Candidates who meet the above criteria are encouraged to apply. Please email CV, statement of research interests, copies of previous publications, and the names and contact information for three references to Ryan Smith at rcs4001@med.cornell.edu.

 

Postdoctoral Fellow, Molecular Aging Initiative

Position Summary:

The Englander Institute for Precision Medicine (EIPM) at Weill Cornell Medicine is seeking a postdoctoral fellow with a background in molecular biology or a related field to join our team.  We are seeking a dynamic individual with leadership qualities who will be responsible for designing and executing studies focused on clonal hematopoiesis and model development – to reduce the risk of cancer and cardiovascular disease associated with aging.

 

A priority of the EIPM is to develop innovative new ways of predicting risk of future disease through (i) identification of somatic changes in the peripheral blood such as clonal hematopoiesis via cohort-based and population-based studies (ii) develop targeted clinical trials and pre-clinical models based on these somatic changes; and (iii) change the standard of care and reduce age-related adverse outcomes via drug development. Our research is focused on the utilization of patient samples to ascertain the functional impact of genetic and epigenetic alterations that occur during normal aging and that have known associations with cancer and cardiovascular disease.  Our goal is to translate these findings to the clinic.

 

Responsibilities:

The work will be performed under the supervision of Dr. Pinkal Desai. The candidate will collaborate with a multidisciplinary team composed of basic scientists, computational biologists, pathologists, and medical oncologists, with significant resources for bioinformatics support and studies in human tissues.

The candidate is expected to perform experiments exploring next generation sequencing methods and implementation, clonal hematopoiesis model development, bone marrow microenvironment, bone marrow metabolism, and genetic and epigenetic alterations using a variety of systems including cell lines, co-culture systems, xenografts, and genetically engineered mouse models.  A desire to develop and implement new methodologies is highly advantageous.  There will be numerous opportunities for training to complement current skills, and we envision numerous collaborations with other outstanding scientists.

 

Perform experiments using next generation sequencing, clonal hematopoiesis model development, bone marrow microenvironment, bone marrow metabolism, measurable residual disease post-therapy, and genetic and epigenetic alterations using a variety of systems including cell lines, co-culture systems, xenografts, and genetically engineered mouse models.

 

Qualifications:

Applicants should have experience in a related field, together with a strong publication record, and strong previous research experience in genomics, bioinformatics, or related fields. Experience with several of the following activities would be desirable: characterization of genetically engineered mouse models, work with patient-derived xenografts and culture of primary cells.  Initial salary is commensurate with experience. Applying for independent funding is not required, but is strongly encouraged for the career development of the candidate.

  • MD and/or PhD in biological sciences, biochemistry or related field is required.
  • Minimum 2 years laboratory experience
  • Knowledge, Skills and Abilities:
  • Strong communication skills and an ability to interact well with others
  • Detail-oriented

 

Applications:

Please send Curriculum vitae, personal statement and two letters of recommendation to EIPMadmin@med.cornell.edu

Postdoctoral Fellow, Biomedicine, Zippin Lab

Position Summary

The laboratory of Jonathan Zippin at Weill Cornell Medicine in New York City is seeking highly motivated and talented postdoctoral fellows and research associates to lead several projects including:

  • The role of melanosome pH in normal and malignant melanocyte biology in the skin and eyes.
  • The interplay between mitochondrial and melanin metabolism.
  • The effects of distinct cAMP microdomains on cancer growth and response to therapy.

These projects are funded by recent grants from the NIH, foundations, and industry.

 

We use a variety of cellular and mouse model systems and technologies such as microscopy, high-throughput sequencing techniques, and LC/MS.

 

Our lab works closely with groups within the Meyer Cancer Center; the Englander Institute of Precision Medicine at Weill Cornell Medicine; and Memorial Sloan Kettering Cancer Center. We are also actively involved in the development of new therapeutics for dermatologic diseases and cancer through the Tri-Institutional Therapeutics Discovery Institute at Weill Cornell Medicine.

 

Relevant publications:

Zhou, D., Ota, K., Nardin, C., Feldman, M., Widman, A., Wind, O., Simon, A., Reilly, M., Levin, LR., Buck, J., Wakamatsu, K., Ito, S. and Zippin, JH. (2018). Mammalian pigmentation is regulated by a unique cAMP-dependent mechanism that controls melanosome pH. Sci Signal. 11, Issue 555, eaau7987. https://stke.sciencemag.org/content/11/555

 

Chen Q, Zhou D, Abdel-Malek Z, Zhang F, Goff PS, Sviderskaya EV, Wakamatsu K, Ito S, Gross SS, Zippin JH. Measurement of melanin metabolism in live cells by [U-13C]-tyrosine fate tracing using LC-MS. J Invest Dermatol. 2021 Feb 4:S0022-202X(21)00078-6. doi: 10.1016/j.jid.2021.01.007. https://www.sciencedirect.com/science/article/pii/S0022202X21000786?via%3Dihub

 

Candidates must possess strong research skills in Cell and Molecular Biology; Microscopy; and be comfortable working with mice. A background in computational biology, bioinformatics, LC/MS, tumor models, and/or live cell imaging is preferred. This position represents an opportunity to join a world-class team at a top-rated medical center. Please visit our website at https://zippinlab.weill.cornell.edu for more information about our research goals and environment. We are looking to fill this position in the next few months.

 

Interested applicants should send their curriculum vitae to:

 

Jonathan Zippin, MD PhD

Vice Chair of Research
Department of Dermatology

Joan and Sanford I. Weill Medical College of Cornell University

1305 York Avenue, 9th Floor

New York, NY 10021

jhzippin@med.cornell.edu

 

Weill Cornell Medical College is an equal opportunity/Americans with Disabilities Act employer

Informatics & Computational Biology

Our faculty and staff are distinguished scientists who specialize in designing computational methods for extracting insights from next-generation sequencing data.

Senior Bioinformatics Analyst

Position Summary:

Leads the development, testing and maintenance of analytical pipelines used to support genomic testing based on whole exome sequencing and other tests within the lab of world-renowned computational biologist Olivier Elemento, Ph.D., Director of the Englander Institute for Precision Medicine.

 

Responsibilities:

  • Responsible for biostatistical analysis and data interpretation for large data sets. Performs genomic analyses including mutation analyses, integrates datasets and generates figures summarizing results and key findings.
  • Implements pipelines for detecting and annotating mutations from single patient, whole-exome sequencing datasets.
  • Implements primary processing pipeline and quality control; runs pipeline(s) on all new samples.
  • Implements procedures for disaster recovery and resuming failed jobs.
  • Works closely with bioinformatics team(s) to define specifications for information systems, relational datasets, and sequencing analysis.
  • Develops novel algorithms and tools for high throughput data analysis.
  • Explores new computing platforms, performs benchmarking and implements data sharing.
  • Performs other related duties as assigned.

 

Qualifications:

  • Bachelor’s Degree in related field
  • S. in molecular biology, genetics, bioinformatics, biomedical engineering or computer science desired. MS or PhD in systems biology, bioinformatics or computer biology is highly desired.
  • Approximately 3 years of related experience.
  • Bioinformatics analysis expertise as demonstrated by multiple published papers.
  • Excellent programming expertise in at least one of the following languages: C, C++, Java or Python.
  • Experience in biology and/or cancer biology is preferred.
  • Experience working in an academic environment is highly desired.
  • Previous experience in designing and building bioinformatics workflows preferred.
  • Previous experience analyzing and summarizing genomic datasets preferred.
  • Excellent communication skills.
  • Excellent understanding of biology and biomedicine.
  • Ability to work with limited supervision.

 

Applications:

Applications: Please send Curriculum vitae, personal statement and two letters of recommendation to EIPMadmin@med.cornell.edu

Bioinformatics Analyst

Position Summary:

At the Englander Institute for Precision Medicine (EIPM), our mission is to use Next Generation Sequencing (NGS) data to give late-stage cancer patients therapeutic options to prolong and better their quality of life. In just four years we have built a CLIA-approved genomics test that has already been used on over 800 patients. As a Bioinformatics Analyst at IPM, you will be able to immediately impact and build data products aimed at expanding the scope of our genomics platform. You will get to create new ways of improving aspects of the genomics platform such as sample collection, sequencing, genomic data analysis, and reporting. You will also get to work with a diverse team of software engineers, bioinformaticians, researchers, and physicians, and create products that deepen our understanding of how cancers evolve and the best treatment options for them.

 

The Bioinformatics Analyst will perform statistical and integrative data analysis for genomics and clinical data for the Institute for Precision Medicine (EIPM). You will arm IPM with data and insights to help enhance the clinical sequencing portfolio. You’ll be focused on improving our Whole Genome analysis pipeline (SNVs, CNVs, Structural Variant calling) for our Whole Genome test. You should be passionate about finding inefficiencies in how we generate clinically actionable insights, and enjoy brainstorming and building workflow solutions.

 

Responsibilities:

  • Conducting and maintaining systematic documentation of clinical-enterprise software pipelines for compliance using (git/svn/etc.)
  • Assisting in the development of new software tools and build pipelines for novel bioinformatics analyses
  • Assisting in development and maintenance of genomic and clinical databases
  • Creating web user interfaces for to explore large data stores, combining genomic and clinical data and statistical analyses to help other IPM team members understand insights form theses data stores
  • Performing statistical and integrative data analysis on genomics and clinical data

 

Qualifications:

  • Demonstrated ability to run computationally intensive jobs on HPC and Cloud computing environments
  • Previous experience in designing and building bioinformatics workflows
  • Proficiency in programming in Java, C, C++
  • Experience in web user interface applications and database design
  • Knowledge of clinical IT systems (OMOP, HL7 messaging, etc.)
  • Driven and Self-motivated. Willingness to tackle and drive execution of challenging projects
  • Ability to learn and deliver work in fast-paced and diverse environment
  • Comfortable with communicating and working alongside a diverse team of scientists and medical professionals
  • BS in Bioinformatics, Biomedical Engineering, Computer Science or Related Field
  • Minimum 3 years experience working with next generation sequencing data and relevant tools (GATK, samtools, BWA, TopHat, STAR,etc.)
  • Knowledge and proficiency of UNIX
  • Proficiency in at least one scripting language : (R, Ruby, Python, Perl)
  • Experience using Git/SVN

 

Applications:

Applications: Please send Curriculum vitae, personal statement and two letters of recommendation to EIPMadmin@med.cornell.edu

Front End Developer

Position Summary

At the Englander Institute for Precision Medicine (EIPM), we are a multidisciplinary team of researchers, scientists, and physicians focused on integrating software, data, and our collective experiences to provide better care for our patients, pave the path to new discoveries and teach the future of medicine. Leveraging bleeding edge technology from Next Generation Sequencing (NGS) to Cloud Computing we develop software solutions and process vast amounts of data to offer clinical grade genomic tests spanning over 21000 genes to improve care for late-stage cancer patients. We see precision medicine at the crossroad of technology and medicine and seek champions to join our ever-expanding team, disrupt and redefine medicine.

 

Job Responsibilities

  • Gather user requirements, design, research, implement and maintain software solutions.
  • Collaborate with the rest of the computational team to design and launch new features.
  • Take projects from the design phase to a stable production release that can scale.

 

Basic Qualifications

  • Proficient in Web technologies: HTML5, CSS3/Sass, JavaScript
  • Thorough Experience in at least one Front End JavaScript Framework: Angular 2+, React, Vue.JS
  • Demonstrated experience working with source control (Git preferred) and participating in Agile (Scrum) development.
  • Familiarity on building and working with APIs (RESTful, GraphQL).
  • Experience with Relational (MySQL is preferred) and NoSQL databases.
  • Strong verbal and written communication skills.
  • Willingness to tackle any challenge, even if not directly relevant to core competencies.
  • Ability to adjust to business change; common types of changes include new requirements, evolving goals and strategies, and emerging technologies.

 

Preferred Qualifications

  • Graduate Degree in Computer Science or related field.
  • Demonstrated experience with container technologies such as Docker and Kubernetes are considered a strong plus.
  • Experience with prototyping tools such as Adobe XD, Sketch, Figma, InVision is considered a strong plus.
  • Experience with Photoshop is considered a plus.

Weill Cornell Medicine is a comprehensive academic medical center that is committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies.

Located in the heart of the Upper East Side’s scientific corridor, Weill Cornell Medicine’s powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria, and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork-Presbyterian/Lower Manhattan Hospital, and NewYork-Presbyterian/Queens.

At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients – the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity/Minorities/Females/Vet/Disabled employer.

 

To Apply

To apply for this position please visit our Linked In page.

Machine Learning Analyst

Position Summary

Responsible for developing, designing, and implementing tools for machine learning applications and retraining systems. Ultimate goal is to shape and build efficient self-learning applications.

Job Responsibilities

  • Studies and transforms data science prototypes.
  • Designs machine learning systems.
  • Researches and implements appropriate Machine Learning (ML) algorithms and tools.
  • Develops machine learning applications according to requirements.
  • Selects appropriate datasets and data representation methods.
  • Develops and executes image analysis tools for Machine Learning (ML) applications.
  • Runs machine learning tests and experiments.
  • Performs statistical analysis and fine-tuning using test results.
  • Trains and retrains systems when necessary.
  • Extends existing Machine Learning (ML) libraries and frameworks.
  • Keeps abreast of developments in the field.

Education

  • Bachelor’s Degree in related field

Experience

Bachelor’s degree in Computer Science, Mathematics or similar field. Master’s degree is a plus.

Proven experience as a Machine Learning Analyst or similar role.

Significant experience with image processing and image analysis.

Knowledge of data science and software engineering desired.

Knowledge, Skills and Abilities

  • Exceptional skills in statistics and programming.
  • Understanding of data structures, data modeling and software architecture.
  • Deep knowledge of math, probability, statistics and algorithms.
  • Ability to write robust code in Python, Java and R.
  • Familiarity with machine learning frameworks (like Keras, TensorFlow, or PyTorch) and libraries (like scikit-learn).
  • Excellent communication skills (both verbal and written).
  • Ability to work in a team environment, be self-motivated, possess strong organizational skills, and work on multiple tasks concurrently.
  • Strong analytical and problem-solving skills.

Weill Cornell Medicine is a comprehensive academic medical center that is committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies.

Located in the heart of the Upper East Side’s scientific corridor, Weill Cornell Medicine’s powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria, and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork-Presbyterian/Lower Manhattan Hospital, and NewYork-Presbyterian/Queens.

At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients – the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity/Minorities/Females/Vet/Disabled employer.

 

To Apply

To apply for this position please visit this link.

Laboratory, Sequencing, Innovation

As pioneers in the field of precision medicine, the EIPM is continuously working to accelerate discoveries and drive innovation.

Research Program Specialist

Position Summary

Under general direction, the assists in the administration, execution, development, and overall management, clinical research functions and programs.

 

Job Responsibilities

  • Coordinates research studies in compliance with federal regulations, GCP guidelines, and internal policies.
  • Responsible for subject management. Works closely with the research team to facilitate the recruitment, enrollment, and data collection for clinical research studies.
  • Assists with eligibility assessment and obtaining written informed consent, as appropriate. Performs central subject registration for specified research studies.
  • Coordinates the data management of research studies within the institution and with collaborating institutions in compliance with federal regulations, GCP guidelines, and internal policies.
  • Develops and maintains study documentation and databases. Performs data collection and entry, as needed. Ensures data quality and integrity throughout the life of the study.
  • Facilitates sample collection, processing and storage activities as required by protocols.
  • Compiles data reports and progress reports. Generates and disseminates study documents to investigators and/or program directors.
  • Assists with data and research analyses for publications and presentations.
  • Contributes to and writes research findings for lectures, manuscripts, publications, grants, and other documents.
  • Under the direction of the PI, drafts investigator-initiated research protocols and amendments.
  • Provides training and mentorship to junior and new staff.
  • Attends conferences and provides guidance to clinical staff.

 

Experience
  • Bachelor’s Degree in Science, Healthcare, or a related field.
  • 2+ years of prior research experience in a health-related clinical or research setting.
  • Research experience in an academic health center.

 

Knowledge, Skills and Abilities

  • Knowledge in Food and Drug Administration (FDA) and Office for Human Research Protections (OHRP) regulations, and International Conference on Harmonization (ICH) Good Clinical Practice (GCP) guidelines.
  • Excellent written and verbal communication skills.
  • Demonstrated strong communication and interpersonal skills; demonstrated ability to interact with multiple constituencies and exercise “people skills”.
  • Demonstrated proficiency with MS Office Suite and database applications.
  • Demonstrated organizational skills and ability to pay close attention to detail.
  • Demonstrated critical thinking and analytical skills.
  • Demonstrated ability to multi-task and prioritize in a fast-paced environment.
  • Demonstrated ability to remain focused despite frequent interruptions.
  • Ability to treat confidential information with utmost discretion.
  • Ability to exercise standards of professionalism, including appearance, presentation and demeanor.
  • Demonstrated ability to work effectively in a collaborative manner with all departmental faculty and staff, as well as other institutional representatives.
  • Ability to work independently and within a team.

 

Education: Bachelor’s Degree in related field

Working Conditions/Physical Demands: Standard office work.

To Apply: Please visit the Weill Cornell Medicine Human Resources website and search for Requisition ID 52401.

# # #

Data Specialist

Position Summary

Under supervision, responsible for creating and managing databases, as well as for merging data as needed and providing database support.

 

Job Responsibilities

  • Designs and maintains relational databases, including developing programs and coding to support ease of data entry, management, and automated reports; may involve a limited amount of data entry and data cleaning.
  • Generates and distributes summary reports in a timely manner, prioritizing multiple requests and maintaining a supportive relationship with all users.
  • Assists with the creation of parameters and design of report output.
  • Performs regular audits to ensure data integrity and quality.
  • Assists in the creation of policies and procedures that efficiently enhance data integrity.
  • Maintains knowledge of industry standards and best practices to ensure all deliverables meet those standards.
  • Performs other related duties as assigned.

 

Experience

  • Approximately 2-4 years of experience with data entry, querying and reporting from relational databases.
  • Fluent in the use of relational databases.

 

Education: Associate’s Degree

Knowledge, Skills and Abilities

  • Clear demonstrations of technical, analytical, organizational, problem solving, and communication skills.
  • Ability to work with others in a multi-functional team.
  • Excellent attention to detail, patience, and a positive, customer-centric attitude.
  • Fluency with relational and multidimensional database concepts; experience in SQL, R, SAS, REDCap and MS Excel.
  • Demonstrated ability to develop proficiency with unfamiliar toolsets and seek out new learning and training opportunities.
  • Demonstrated professionalism and ethical standards for handling confidential information.

 

Working Conditions/Physical Demands: Standard office work

To Apply: Please visit the Weill Cornell Medicine Human Resources website and search for Requisition ID 53204.

# # #

Translational Research Specialist (Organoid Platform)

Translational Research Specialist opportunity 

Location: Upper East Side

Org Unit: Olivier Elemento Lab

Work Days: Weekdays and some weekends

Exemption Status: Non-Exempt

Salary Range: $29.26 – $43.19

*As required under NYC Human Rights Law Int 1208-2018 – Salary range for this role when Hired for NYC Offices

Position Summary

Responsible for overseeing and coordinating laboratory activities associated with specimen processing and novel EIPM research assays and processes. Under direction of platform managers, is responsible for facilitating downstream translational research sample prioritization and assay execution. This role oversees experimental strategies, ensures that workflow design is adequate and efficient for key processes, and may perform selected procedures in the wet lab associated with molecular, genomic, histology, organoid, and/or biobanking methods, including but not limited to sample preparation, tissue culturing and processing, quality control, and biospecimen storage and tracking.

Job Responsibilities

  • Oversees and assists in developing protocols for novel research processes, such as sample extraction and QC, tissue culture protocols, tissue optimization, and biobanking. Designs training materials for new employees to ensure proper use of all protocols.
  • Facilitates downstream experimental strategies or analyses from translational research samples. Coordinates assay prioritization and execution with platform managers.
  • Oversees translational research sample receipt and downstream processing and accessioning from WCM/NYP clinics and external institutions.
  • May be responsible for overseeing next-generation biobanking workflows and facilitating the receipt, storage, cataloguing and shipment of samples within and between institutions.
  • Performs advanced analyses to measure research assay performance and efficiency. Prepares and maintains detailed QC documentation logs and laboratory notebooks for progress reporting and experimental tracking for the platform.
  • Evaluates results of quality control trends and implements corrective action when needed. May independently or semi-independently, design and carry out experiments.
  • Ensures that storage units and laboratory databases are being maintained and monitored appropriately. Performs routine equipment maintenance, as needed.
  • May perform various molecular biology procedures, such as PCR, DNA/RNA extractions, protein and DNA electrophoresis, blood processing, cloning, tissue culture, and drug experiments.
  • Enters experimental, technical, and QC data into the laboratory information management system (LIMS). Designs and centralizes SOP modifications and communicates to software team for systems integration.
  • Conducts library research and literature searches using various computer systems. Assists in editing scientific publications, abstracts and/or posters.
  • Assists in the orientation and training of new investigators, fellows, residents, and technical staff in the use of equipment, products and experimental techniques.
  • Provides working supervision to junior laboratory staff as needed. Directs research support for staff to execute proper triaging of samples for downstream procedures.
  • Ensures a clean working area and prepares laboratory for next day’s processing requirements.
  • Ensures that safe laboratory practices are followed, including the use and disposal of chemicals and hazardous materials.
  • May need to assist in the orientation and training of new investigators, fellows, residents, and technical staff and/or provide working supervision to lower level laboratory staff.
  • May run routine biochemistry assays including western blotting and RT-PCR.

Education

  • Bachelor’s Degree

Experience

  • Approximately 3-5 years of related work experience within a laboratory.
  • Prior experience handling biological specimens is required.
  • Prior experience in molecular biology techniques such as sample extraction and tissue culture is required.

Knowledge, Skills and Abilities

  • Demonstrated organizational skills and ability to pay close attention to detail.
  • Ability to multi-task and handle multiple competing priorities.
  • Demonstrated leadership skills and ability to mentor others.

Working Conditions/Physical Demands

  • Standard laboratory conditions.
  • This position may require standing or sitting for long periods of time.
  • This role may require working within Biologic Safety Level 1 and 2.

 

To Apply: Please send a cover letter and resume to Ms. Jenna Moyer, Lab Supervisor – Ex vivo models: jem4012@med.cornell.edu 

# # #

Translational Research Technologist II (Organoid Platform)

Translational Research Technologist II opportunity

Location: Upper East Side

Org Unit: Olivier Elemento Lab

Work Days: Monday-Friday

Exemption Status: Non-Exempt

Salary Range: $29.62 – $41.81

*As required under NYC Human Rights Law Int 1208-2018 – Salary range for this role when Hired for NYC Offices

Position Summary

Plays a critical role within the Englander Institute of Precision Medicine (EIPM) Laboratory. Responsible for carrying out laboratory activities associated with specimen processing and novel EIPM research assays and processes. Under direction of platform managers, assists in centralizing key workflows, and both independently and collaboratively perform selected procedures in the wet lab associated with molecular, genomic, histology, organoid, and/or biobanking methods, including but not limited to sample preparation, tissue culturing and processing, quality control, and biospecimen storage and tracking.

Job Responsibilities

  • Assists with experimental design and carries out experiments related to precision medicine projects.
  • Analyzes and interprets experimental results and provides input related to subsequent experimental designs.
  • Prepares and maintains detailed QC documentation, logs, and laboratory notebooks for progress reporting and experimental tracking for the platform.
  • May perform various molecular biology procedures, such as PCR, DNA/RNA extractions, protein and DNA electrophoresis, blood processing, cloning, tissue culture, and drug experiments.
  • May prepare tissue specimens according to specific research protocols, perform histologic staining and tissue sectioning, and prepares slides from tissue sections for microscopic examination and diagnosis.
  • Enters experimental, technical, and QC data for translational research biospecimens into the Laboratory Information Management System (LIMS).
  • Under supervision, maintains inventory of research specimens in laboratory databases and availability of space in storage units.
  • Receives and verifies translational research samples for downstream processing and accessioning from WCM/NYP clinics and external institutions.
  • May be responsible for overseeing next-generation biobanking workflows and facilitate the receipt, storage, cataloguing and shipment of samples within and between institutions.
  • Supports protocol design of new techniques to assist in overall laboratory efficiency.
  • Conducts library research and literature searches using various computer systems. Assists in editing scientific publications, abstracts and posters.
  • May assist in the orientation and training of new investigators, fellows, residents, and technical staff in the use of equipment, products and experimental techniques.
  • Ensures a clean working area and is responsible for washing and storing glassware.
  • Ensures that safe laboratory practices are followed, including the use and disposal of chemicals and hazardous materials.
  • Ensures that facilities and equipment are in optimal and proper working condition. Coordinates preventative maintenance and repairs as needed. May monitor storage units such as -80 freezers to ensure they are operating at appropriate temperature.

Education

  • Bachelor’s Degree

Experience

  • Approximately 2 years of related work experience within a laboratory.
  • Prior experience handling biological specimens is strongly preferred.
  • Prior experience in molecular biology techniques such as sample extraction and tissue culture is desired.

Knowledge, Skills and Abilities

  • Demonstrated organizational skills and ability to pay close attention to detail.
  • Ability to multi-task and handle multiple competing priorities.

Working Conditions/Physical Demands

  • Standard laboratory conditions.
  • This position may require standing or sitting for long periods of time.
  • This role may require working within Biologic Safety Level 1 and 2.

 

To Apply: Please send a cover letter and resume to Ms. Jenna Moyer, Lab Supervisor – Ex vivo models: jem4012@med.cornell.edu 

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