| Title | Cancer stem cell immunoediting by IFNγ. |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Galassi C, Galluzzi L |
| Journal | Cell Death Dis |
| Volume | 14 |
| Issue | 8 |
| Pagination | 538 |
| Date Published | 2023 Aug 21 |
| ISSN | 2041-4889 |
| Keywords | Humans, Neoplasms |
| Abstract | The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy. |
| DOI | 10.1038/s41419-023-06079-2 |
| Alternate Journal | Cell Death Dis |
| PubMed ID | 37604810 |
| PubMed Central ID | PMC10442329 |
| Grant List | U54 CA274291 / CA / NCI NIH HHS / United States R01 CA271915 / CA / NCI NIH HHS / United States |