Title | Bacterial antigens unleash tumor-targeting immunity. |
Publication Type | Journal Article |
Year of Publication | 2023 |
Authors | Boeck N, Trajanoski Z, Galluzzi L |
Journal | Cell Host Microbe |
Volume | 31 |
Issue | 12 |
Pagination | 1945-1947 |
Date Published | 2023 Dec 13 |
ISSN | 1934-6069 |
Keywords | Antigens, Bacterial, Colorectal Neoplasms, Epitopes, Gastrointestinal Microbiome, Humans, Immunity |
Abstract | The composition of the gut microbiome has been shown to influence disease outcome in patients with colorectal cancer (CRC). In a recent Nature Biotechnology article, Wang et al. demonstrate that killing CRC-associated bacteria with a liposomal antibiotic elicits CRC-targeting immune responses of therapeutic relevance as a consequence of epitope mimicry. |
DOI | 10.1016/j.chom.2023.11.001 |
Alternate Journal | Cell Host Microbe |
PubMed ID | 38096784 |