Englander Institute for Precision Medicine

Bacterial antigens unleash tumor-targeting immunity.

TitleBacterial antigens unleash tumor-targeting immunity.
Publication TypeJournal Article
Year of Publication2023
AuthorsBoeck N, Trajanoski Z, Galluzzi L
JournalCell Host Microbe
Date Published2023 Dec 13
KeywordsAntigens, Bacterial, Colorectal Neoplasms, Epitopes, Gastrointestinal Microbiome, Humans, Immunity

The composition of the gut microbiome has been shown to influence disease outcome in patients with colorectal cancer (CRC). In a recent Nature Biotechnology article, Wang et al. demonstrate that killing CRC-associated bacteria with a liposomal antibiotic elicits CRC-targeting immune responses of therapeutic relevance as a consequence of epitope mimicry.

Alternate JournalCell Host Microbe
PubMed ID38096784

Weill Cornell Medicine Englander Institute for Precision Medicine 413 E 69th Street
Belfer Research Building
New York, NY 10021