
Dear Members of the Englander Institute,Last week we kicked off the 6-week Summer Program for high school students that we jointly administer with our friends from the Meyer Cancer Center! The students will partner with EIPM faculty mentors, work on individual and group projects, attend EIPM events, including seminar series, working groups and journal clubs, weekly lectures. Thanks to everyone who helped plan the summer program and to all our mentors!
Our friends from Cure51 are creating the first worldwide database of cancer survivors and I spoke with them via zoom recently about a shared goal of making every cancer patient a longterm responder. Please visit our X (Twitter) feed, Facebook page or visit our YouTube channel (shorts category) to see a series of short videos about our shared commitment to research and patient care.
Last chance to participate! Clinical Director Dr. Cora N. Sternberg is still recruiting people aged 50 and older, with no active cancer in the last 3 years, to participate, at no cost, in the Grail Pathfinder study for early-detection of cancer, which was recently featured in The Wall Street Journal. For more information about the study please email: grailstudy@med.cornell.edu
I hope you enjoy reading about our recent departmental accomplishments, including new awards, media coverage of our work, participation in major conferences & meetings, and impressive publications by a range of EIPM colleagues.
Below please find links to interesting funding opportunities with fast-approaching deadlines: Artificial Intelligence from Cooperative AI (deadline July 30th); Innovative Cancer Research from Damon Runyon (deadline July 8th); Prostate Cancer from Pfizer Global Medical Grants (deadline July 18th); and Cervical cancer from Pfizer Global Medical Grants (deadline August 22nd).
Thank you again for your continued hard work and dedication to our mission.
Sincerely,
Olivier Elemento, Ph.D.
News Coverage & Awards Chief Research Officer Dr. Bishoy Faltas provided the UroToday Expert Commentary, "Prognostic Value of Longitudinal ctDNA in Patients with Muscle-Invasive Bladder Cancer Undergoing Radical Cystectomy," on June 11th.
New research by Dr. Dan Landau was covered in the Medical Device Network's June 17th article, "Weill Cornell reports new AI technology predicts cancer recurrence in study. Utilising machine learning (ML), the technology can help identify circulating tumour DNA with high accuracy." Dr. Landau was also featured in the June 14th Inside Precision Medicine article "AI-Powered Liquid Biopsy Delivers Ultrasensitive Cancer Detection." Dr. Scott T. Tagawa participated in a video interview with UroToday, "Dose-Escalation of Lutetium PSMA: Final Results from a Phase I/II Trial," that ran on June 13th. OncDaily ran a related story, "ASCO24 Updates: Innovative 177Lu-PSMA-617 Therapy: Enhanced Survival in Prostate Cancer," on June 14th.
Alexandros Sigaras and I were featured in a new Impact Magazine feature article, "The Sounds of Science, marrying acoustic insights from ornithology with artificial intelligence, doctors and researchers at Weill Cornell Medicine hope to use the human voice to screen for disease." The Bridge2AI project is fascinating, and includes partners from the University of South Florida, the NIH, and the Cornell Lab of Ornithology.Dr. Laura Santambrogio was a guest on The Chikly Health Institute's video blog on June 28th discussing recent progress from her lab in the field of lymphology.
Events
Director Olivier Elemento, Ph.D. delivered the Keynote, "Genomes, Avatars and AI: The Future of Personalized Medicine," on June 20th at the Scholars in BioMedical Sciences Symposium hosted by the Renaissance School of Medicine at Stony Brook University!Thanks to medical student Kyle Finos for his fascinating and well-received June 21st EIPM AI Working Group presentation, “Modeling Highly Multiplexed Imaging Data with Self Supervised Deep Learning – Challenges and Approaches.”
Our new friends Molly Bonakdarpour and Dr. Erandi de Silva (third from left) from the venture capital firm Drive Capital visited us on June 12th for a tour of our facilities and briefing by members of our faculty, including Dr. Ben Hopkins and myself.
Dr. Manish A. Shah from WCM's GI Oncology department delivered Heme Onc Grand Rounds on June 18th, providing a round-up of the recent ASCO24 meeting.Dr. Bishoy Faltas presented a WCM Dept. of Pharmacology Seminar, “The Interplay Between Mutagenesis and Extrachromosomal DNA Shapes Urothelial Cancer Evolution," on June 19th.
Dr. Daniela Guevara presented two cases referred by Clinical Director Dr. Cora N. Sternberg at our most recent Precision Medicine Research Conference on June 27th. Dr. Iman Hajirasouliha will present in September at the 2024 AI Fertility World Conference in Croatia.
The Harvard T.H. Chan School of Public Health's Program in Quantitative Genomics will host its 18th annual conference, “AI for Genomics and Health,” in Boston this October and feature speakers including EIPM Director Olivier Elemento, PhD.
Publications"Artificial INtelligence to Support Informed DEcision-making (INSIDE) for Improved Literature Analysis in Oncology," was published in European Urology Focus on June 13th by Clinical Director Dr. Cora N. Sternberg, and Dr. Andrea Sboner from the Pathology and Laboratory Medicine department and the EIPM.
"TRIUMPH: phase II trial of rucaparib monotherapy in patients with metastatic hormone-sensitive prostate cancer harboring germline homologous recombination repair gene mutations," was published in The Oncologist on June 17th by Clinical Director Dr. Cora N. Sternberg and colleagues. "Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment," was published in Nature Medicine on June 14th by Dr. Dan Landau, with Drs. Nasser Altorki and Ashish Saxena. The paper was covered by Inside Precision Medicine on June 14th and the Cornell Chronicle on June 18th.
"Multinational, Multicenter Evaluation of Prostate Cancer Tissue in Sub-Saharan Africa: Challenges and Opportunities," was published in JCO Global Oncology on June 13th by Drs. Brian D. Robinson and Juan Miguel Mosquera from the Pathology and Laboratory Medicine department and the EIPM."Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load," was published in Cell Reports on June 25th, by Dr. Laura Santambrogio and colleagues.
"Optimization of Fluorescence In Situ Hybridization Protocols in the Era of Precision Medicine," was published in Current Protocolson June 25th by Dr. Juan Miguel Mosquera, with Drs. Sarah Kudman, Alissa Semaan, David C. Wilkes, Majd Al Assaad from the Pathology and Laboratory Medicine Department and the EIPM, our former EIPM colleague Dr. M. Laura Martin, and EIPM Director Olivier Elemento, PhD."Whole Genome Landscape Analysis of Homologous Recombination Deficiency in a Pan-Cancer Cohort," a medRxiv preprint on June 30th, by Drs. Juan Miguel Mosquera, Majd Al Assaad, and Andrea Sboner from the Pathology and Laboratory Medicine department and the EIPM; with Daniela Guevara, MD, Marvel Tranquille, MS, Abigail King, BS, John Otilano, BS, Alissa Semaan, MS, Michael Sigouros, BS, Jyothi Manohar, MPH, Hui-Hsuan Kuo, BS, David C. Wilkes, PhD, Eleni Andreopoulou, MD, Eloise Chapman-Davis, MD, Scott T. Tagawa, MD, Allyson J. Ocean, MD, Manish Shah, MD, Cora N. Sternberg, MD, Kevin Holcomb, MD, David M. Nanus, MD, and Director Olivier Elemento, PhD from the EIPM.
"Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer," was published in Nature Medicine on June 28th by Hiranmayi Ravichandran, Director Olivier Elemento, Ph.D., and colleagues.
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