Englander Institute for Precision Medicine
Dr. Jan Krumsiek

A person’s “bioenergetic age” – or how youthfully their cells generate energy – might be a key indicator of whether they’re at risk of developing Alzheimer’s disease, new research from Weill Cornell Medicine shows.

The study, published Feb. 24 in Nature Communications, suggests healthy living can turn back the bioenergetic clock for some people, helping them fend off...

A person’s bioenergetic clock ticks forward based on genetics, but having a healthy lifestyle—such as eating a plant-based diet and exercising—may help keep Alzheimer's symptoms at bay. Credit: Shutterstock
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A colorized image of adult mobilized blood stem cells (small and roundish) into which Fli-1 modified mRNA has been introduced, expanding on top of engineered vascular endothelial cells.

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators. The discovery could lead to more effective bone marrow transplants and gene therapies.

A colorized image of adult mobilized blood stem cells (small and roundish) into which Fli-1 modified mRNA has been...