Dear Members of the Englander Institute,
EIPM colleagues, who are also affiliated the Meyer Cancer Center and the Pathology and Laboratory Medicine departments, including Drs. Juan Miguel Mosquera, Cora N. Sternberg and David Nanus, collaborated to save the life of an 81-year-old former minor league baseball player in a new EIPM website story, "How a novel genomic analysis leveraged whole-exome and RNA sequencing to save the life of an elderly patient." We hope you enjoy the article!
Thanks to everyone who joined us on July 9th for "The New York CyTOF Symposium" we hosted with our friends from Standard BioTools! It was very engaging to join with fellow experts and researchers in the CyTOF and Imaging Mass Cytometry communities to discover how high-parameter CyTOF and IMC are transforming clinical research and improving human health.
Congratulations to our inaugural Bridge2AI Voice Summer School class! Students spent the summer with WCM faculty, including co-program leader and Assistant Professor of Otolaryngology Dr. Anaïs Rameau, and staff, conducting independent research projects and presented to their cohort, participating Bridge2AI sites, friends, families, and PIs.
I hope you enjoy reading about our recent departmental accomplishments, including new awards, media coverage of our work, participation in major conferences & meetings, and impressive publications by a range of EIPM colleagues.
Below please find links to interesting funding opportunities with fast-approaching deadlines: Breast Cancer from the US Department of Defense (deadline August 6th); Recurrent/metastatic Cervical Cancer from Pfizer Global Medical Research (deadline August 22nd); Faculty Advancement & Research Mentorship Program from WCM's Office of the Dean and Clinical & Translational Science Center (September 6th); and the Youth Enjoy Science Research Education Program of the National Cancer Institute (applications due September 27th).
Thank you again for your continued hard work and dedication to our mission.
Sincerely,
Olivier Elemento, Ph.D.
News Coverage & Awards 
We hope you'll congratulate Dr. Bishoy Faltas, our Chief Research Officer, on earning a $300,000 2024 Research Innovation Award from the Bladder Cancer Advocacy Network! Dr. Faltas also provided the Expert Commentary "Efficacy of FGFR Inhibitor Derazantinib in Metastatic Urothelial Carcinoma," published in UroToday on July 8th.
Dr. Cora N. Sternberg was interviewed for the UroToday video, "Navigating the Shift to Enfortumab Vedotin and Pembrolizumab in Advanced Urothelial Cancer: Key Considerations for Clinicians," posted on July 9th.
News coverage of Dr. Lisa Newman earning The Gianni Bonadonna Breast Cancer Award that acknowledges her dedication and contributions to the field of global oncology continued with a story in the July 2024 edition of The Oncology Times.
Our Chief Research Officer Dr. Bishoy Faltas provided the following UroTodayExpert Commentary: "Efficacy of FGFR Inhibitor Derazantinib in Metastatic Urothelial Carcinoma," on July 8th, "Efficacy of Cretostimogene Grenadenorepvec and Pembrolizumab in BCG-Resistant NMIBC," on July 19th; and "The Effects of circPKN2 on Ferroptosis in Bladder Cancer," on July 23rd. 
WNBC New York aired an inspiring story on July 14th, "An Eagle Scout designs VR headsets using AI for use by very sick children," about a young man who used his tech skills to help children in the same hospitals where his brother died of cancer, and featuring our colleague Dr. Jeffrey Greenfield.
Dr. Scott T. Tagawa was interviewed for the Targeted Oncologyarticle "Dr. Tagawa discusses the potential benefits of antibody-drug conjugates in urothelial cancer while acknowledging the need for more education and experience among physicians to optimize their use," on July 12th. 
Dr. Allyson Ocean explained why pancreatic cancer is so hard to treat in a new July 22nd article by SurvivorNet: "For Pancreatic Cancer Patients Like Alex Trebek, New Research Suggests Resistance to Chemotherapy Can Be Reversed & Survival Rates Improved."
Dr. Peter Martin discusses with Medical Stories/PBS the journey of one of his patient’s with mantle cell lymphoma, and the clinical trial that gave him a chance at a cancer-free future.
Dr. Pinkal Desai spoke with the Oncology Learning Network on July 28th and shared expert insight into understanding risk stratification and the range of treatment options available for patients with low- and intermediate-risk myelodysplastic syndrome.
Events
Our EIPM colleague Dr. Jonathan Zippin will present on melanocyte biology at the 2024 Annual Pan American Society for Pigment Cell Research on September 9th at Cornell Tech!
Dr. Sternberg's abstract, "Evaluation of event-free survival as a surrogate endpoint for overall survival in muscle-invasive bladder cancer following neoadjuvant therapy," was just accepted for poster presentation at ESMO 2024, to be held in Barcelona, 13-17 September 2024.
Publications
"Molecular Phenotypes and Potential Therapeutic Targets in Esophagogastric Adenocarcinoma Unearthed by Whole Genome and Transcriptome Analyses," was published as a medRxiv preprint on July 8th by lead authors Dr. Annika Windon from the Pathology and Laboratory Medicine Department & Dr. Juan Miguel Mosquera from Pathology and the EIPM; the EIPM's Marvel Tranquille, Jyothi Manohar, Michael Sigouros, and Drs. Allyson J. Ocean, Director Olivier Elemento, and Manish Shah; with Drs. Nicole Mendelson & José Jessurun from Pathology; and Drs. Majd Al Assaad, Erika Hissong, Justin Mclee, Andrea Sboner, and Juan Miguel Mosquera who have joint affiliations with Pathology and the EIPM.
"Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer," was published in Nature Medicine on July 2nd by Hiranmayi Ravichandran, myself and WCM colleagues.
"A mitochondrial checkpoint to NF-κB signaling," was published in Cell Death & Disease on July 3rd by Dr. Lorenzo Galluzzi and colleagues.
"Association of clonal hematopoiesis and mosaic chromosomal alterations with solid malignancy incidence and mortality," was published in Cancer on July 16th by Dr. Pinkal Desai, Zichan Li, and colleagues. 
"Treatment intensification with novel hormonal therapy in castration-sensitive prostate cancer: Patient identification and clinical rationale," was published in Clinical Genitourinary Cancer by Clinical Director Dr. Cora N. Sternberg and colleagues on July 23rd.
"Integrative Transcriptomic and Single-Cell Protein Characterization of Colorectal Carcinoma Delineates Distinct Tumor Immune Microenvironments Associated with Overall Survival," was published as a preprint in Research Square by lead author Dr. Juan Miguel Mosquera from the Pathology and Laboratory Medicine Department and the EIPM; with EIPM's Bhavneet Bhinder, Junbum Kim, Hiranmayi Ravichandran, Kenneth Wha Eng, Rohan Bareja, Jyothi Manohar, Michael Sigouros, Andre F. Rendeiro, Allyson J. Ocean, Director Olivier Elemento, and Manish A. Shah; Pathology Drs. Erika Hissong & Jose Jessurun; and joint WCM Pathology/EIPM colleagues Drs. Kentaro Ohara, Majd Al Assaad, and Andrea Sboner on July 25th.
"Multi-scale signaling and tumor evolution in high-grade gliomas," was published in Cancer Cell by Dr. Tomer M. Yaron-Barir from the Meyer Cancer Center and the Englander Institute for Precision Medicine on July 8th.
"Serum and CSF metabolomics analysis shows Mediterranean Ketogenic Diet mitigates risk factors of Alzheimer's disease," was published in Metabolic Health and Disease by Drs. Jan Krumsiek, Annalise Schweickart, and Richa Batra on July 1st.
"Epacadostat plus pembrolizumab versus placebo plus pembrolizumab for advanced urothelial carcinoma: results from the randomized phase III ECHO-303/KEYNOTE-698 study," was published by Clinical Director Dr. Cora N. Sternberg as Co-senior author in BMC Cancer on July 25th.
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