July 2025 EIPM Director's Memo
Dear Friends & Members of the Englander Institute,
We are looking for EIPM Journal Club speakers through the end of the year to address topics like precision medicine, genetics, and artificial intelligence in medicine in top tier journals. Please contact Bhavneet Bhinder or Suzanne Jlelaty with questions or ideas.
I hope you enjoy reading about the exciting trade press and mainstream news media coverage of our work, awards to leading investigators like our Clinical Director Dr. Cora N. Sternberg, and research published recently in top-tier journals like Nature Communications and The New England Journal of Medicine!
Thank you again for your continued hard work and dedication to our mission.
Sincerely,
Olivier Elemento, Ph.D.
News Coverage & Awards 
"Reporter battles the odds with cancer. Michael Kaplan, veteran journalist and author, has spent decades telling stories of people who beat impossible odds—at the poker table and in life. But in 2023, his own life took a turn when he was diagnosed with mantle cell lymphoma, a rare and aggressive blood cancer." Learn how Dr. Peter Martin and colleagues successfully treated him." The NY Post, June 14th. 
Congratulations to our Clinical Director Dr. Cora N. Sternberg on earning the Translational Cancer Research journal's Outstanding Author Award for her recent paper, "Does circulating DNA tumor fraction add value to prostate-specific antigen in metastatic castration-resistant prostate cancer?"
"FDA expands Illuccix label to include patient selection for RLT in pre-taxane setting. 'This empowers clinicians to make more informed, personalized decisions earlier in the disease course and access life-prolonging targeted radionuclide therapy for more patients with prostate cancer.' said EIPM Member Dr. Scott T. Tagawa in an interview with Urology Times, June 23rd. Similar articles were published in The ASCO Post on June 24th, Oncology News Central on June 24th, Targeted Oncology on June 25th, OncLive on June 26th, and CureToday on June 27th.
Dr. Olivier Elemento's new blog post, "AI in Hematology: From Promise to Practice--Diagnostics, Decision-Making and the Path to Reimbursement," ran in the June 29th edition of OncoDaily. He also has new substack posts: "Engineering Multi-Agent AI Systems," that published on June 19th; and "Dermatology’s Next AI Chapter" that published on June 23rd.
Weill Cornell Medicine's Summer 2025 Impact Magazine contains interesting articles about research by EIPM colleagues. "Improving Efficiency of IVF," highlights a new artificial intelligence-based system developed by Dr. Iman Hajirasouliha that can accurately assess the chromosomal status of in vitro-fertilized embryos using only time-lapse video images. And "Boosting Response to Cancer Therapy," recaps a new Nature Immunology paper by Dr. Vivek Mittal who discovered that activating a specific metabolic pathway makes antitumor CD8 T cells more likely to stay in an immature, stem-like, “precursor” state.
Events
The EIPM and Meyer Cancer Center's joint 2025 Summer Internship Program began on June 25th! The highly-competitive annual program provides high school and college students with hands-on mentored experiential research experiences related to cancer and precision medicine with the goal to encourage the pursuit of STEM careers. We thank all our mentors for their hard work and dedication to making this another memorable summer, and wish our students a fun and meaningful experience!
Publications
"The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs. Through SAHA, we provide a foundational framework for spatial diagnostics and next-generation precision medicine grounded in a comprehensive human tissue atlas." bioRxiv, published by EIPM colleagues, Drs. Roberto De Gregorio, Olivier Elemento, Alicia Alonso, Shauna Lee Houlihan and colleagues on June 16th. 
"Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer," was published as a Nature Communications article on July 1st by Michael Sigouros, Jyothi Manohar, Abigail King, and Dr. Juan Miguel Mosquera from the Pathology and Laboratory Medicine department and the EIPM.
"International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors," was published in the June 2025 edition of The Journal of Liquid Biopsy by our Scientific Director Dr. Massimo Cristofanilliand colleagues.
"First-Line Camizestrant for Emerging ESR1-Mutated Advanced Breast Cancer," was published in The New England Journal of Medicine on June 1st by our Scientific Director Dr. Massimo Cristofanilli. This research generated significant news media coverage by outlets including: NBC News on June 1st; the Weill Cornell Medicine Newsroom on June 13th; Helio on June 1st, and a Cure article on June 3rd.
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