
Dear Friends & Members of the Englander Institute,Please join me in congratulating our Clinical Director Dr. Cora N. Sternberg on her ScholarGPS Lifetime Highly Ranked Scholar award for bladder cancer & prostate cancer research; and separately for her research in chemotherapy and cancer!
I hope you enjoy reading about our recent departmental accomplishments, including news media coverage of our work, participation in major conferences & meetings, and impressive publications by a range of EIPM colleagues.
Thank you again for your continued hard work and dedication to our mission.
Sincerely,
Olivier Elemento, Ph.D.
News Coverage & Awards Our Chief Research Officer Dr. Bishoy Faltas published the following UroToday Expert Commentary: "BCG Treatment Response in Elderly Patients with Non-Muscle Invasive Bladder Cancer," on April 8th; "A Deep Learning Model to Predict Treatment Response and Recurrence from Whole Slide Images in Non-Muscle-Invasive Bladder Cancer," on April 14th; "Performance Large Language Models in Guiding Bladder Cancer Management," on April 16th; "Long-Term Outcomes of Robot-Assisted Radical Cystectomy in Patients with Non-Muscle-Invasive Bladder Cancer," on April 21st;
A new paper in Nature Methods (see below) by EIPM and Pathology and Laboratory Medicine colleagues was covered by: the Cornell Chronicleon April 14th; the WCM Newsroom on April 11th; Medical Device Network on April 14th; The ASCO Post on April 14th; Business Today on April 14th; and The Organizeron April 16th.Dr. Manish Shah, together with WCM colleagues Drs. Despina Siolas and Gregory F. Sonnenberg, earned a new 2025 PICI Pilot Grant from the Parker Institute for Cancer Immunotherapy and the Meyer Cancer Center to study, "Gut microbiota control of immune suppression in colorectal cancer liver metastases."
The Bridge2AI Voice project, a collaboration between the EIPM and the University of South Florida, continues to make news with "USF doctor enters final year of research to see if AI can detect vocal diseases," broadcast by Fox13 Tampa Bay on April 23rd.The Physicians Weekly April 7th article, "LEOPARD: missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer," covered new research by our colleague Dr. Karsten Suhre.
Events
Dr. Bishoy Faltas presented the interim results of his investigator-initiated trial, "Cell cycLe inhbitiON to Target the EVolution of UrOthelial Cancer (CLONEVO)," at the AACR on April 28th. Clinical Director Dr. Cora N. Sternberg presented her prostate cancer research, "Unenriched baseline CTC-CIN counts are prognostic of overall survival and imaging-based progression-free survival," at the AACR on April 27th.
Publications"Blood-Epigenetic Biomarker Associations with Tumor Immunophenotype in Patients with Urothelial Carcinoma from JAVELIN Bladder 100," a Journal of Allergy and Clinical Immunology preprint on April 11th by Clinical Director Dr. Cora N. Sternberg and colleagues.
"Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling," was published in Nature Methods on April 11th by our Chief Research Officer Dr. Bishoy Faltas, with EIPM colleagues Drs. Ashish Saxena, David Wilkes, Nasser K. Altorki, Olivier Elemento, and Michael Sigouros, Jyothi Manohar, Abigail King, John Otilano; and Pathology and Laboratory Medicine & EIPM colleagues Drs. Giorgio Inghirami and Juan Miguel Mosquera. "The Bridge2AI-voice application: initial feasibility study of voice data acquisition through mobile health," was published in Frontiers in Digital Health on April 14th by Alexandros Sigaras andDirector Olivier Elemento, Ph.D., with colleagues.
"The Use of Artificial Intelligence for Cancer Therapeutic Decision-Making," was published in NEJM AI on April 17th by our Director Olivier Elemento, Ph.D. and Clinical Director Cora N. Sternberg, MD.
"Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation," was published in Cancer Cell on April 17th by Michael Sigouros and colleagues. "Three-dimensional regulatory hubs support oncogenic programs in glioblastoma," was published in Molecular Cell on April 3rd by EIPM Drs. Alexander Martinez-Fundichely, Ekta Khurana, and Howard A. Fine. The paper was covered by the WCM Newsroom on April 23rd.
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