Title | Immunogenicity of cell death driven by immune effectors. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Galluzzi L, Petroni G, Kroemer G |
Journal | J Immunother Cancer |
Volume | 8 |
Issue | 1 |
Date Published | 2020 Apr |
ISSN | 2051-1426 |
Keywords | Cytotoxicity, Immunologic, Immunogenic Cell Death, Killer Cells, Natural |
Abstract | Whether cell death caused by T lymphocytes and natural killer (NK) cells would be immunogenic has been a matter of intense debate. Two back-to-back papers from the Melero's and Pardo's groups have now resolved this conundrum, demonstrating that T and NK cell-mediated cytotoxicity represents indeed a variant of immunogenic cell death. |
DOI | 10.1136/jitc-2020-000802 |
Alternate Journal | J Immunother Cancer |
PubMed ID | 32253221 |
PubMed Central ID | PMC7174067 |