Englander Institute for Precision Medicine
Found 844 results
Author Title Type [ Year(Asc)]
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2025
Nepali PR, Gonzalez-Kozlova E, Anegondi M, Dogra N, Archer M, Chakraborty G, Tewari AK, Hopkins BD, Kyprianou N.  2025.  Effect of TGF-β mediated phenotypic changes on prostate cancer cell anoikis response.. Oncogene.
Tian Y, Bhattacharya R, Yoo S, Jiang F, Park E, Granados GLara, Shen Y, Park K-S, Kaniskan HUmit, Jin J et al..  2025.  Epigenomic analysis identifies DTP subpopulation using HOPX to develop targeted therapy resistance in lung adenocarcinoma.. iScience. 28(5):112387.
Cheng APellan, Widman AJ, Arora A, Rusinek I, Sossin A, Rajagopalan S, Midler N, Hooper WF, Murray RM, Halmos D et al..  2025.  Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling.. Nat Methods.
Sternberg CN, Squifflet P, Saad ED, Burdett S, Fisher D, Kurt M, Teitsson S, May JR, Patel MY, Stoeckle M et al..  2025.  Evaluating surrogates for overall survival in the adjuvant treatment of bladder cancer with chemotherapy.. Urol Oncol.
Sternberg CN, Squires P, Song Y, Wu A, Gao Y, Kataria RS, Li H.  2025.  Evaluation of Event-Free Survival as a Surrogate Endpoint for Overall Survival in Muscle-Invasive Bladder Cancer Following Neoadjuvant Treatment: A Systematic Review and Meta-Analysis.. Oncol Ther.
Rizzo A, Mozgai S, Sigaras A, Rubin JE, Jotwani R.  2025.  Expert Consensus Best Practices for the Safe, Ethical, and Effective Design and Implementation of Artificially Intelligent Conversational Agent (i.e., Chatbot/Virtual Human) Systems in Health Care Applications.. J Med Ext Real. 2(1):209-222.
Montalvo N, Requena F, Capriotti E, Rausell A.  2025.  Federated Learning for the pathogenicity annotation of genetic variants in multi-site clinical settings.. Bioinformatics.
de Bono JS, He M, Shi Z, Nowicka M, Bracarda S, Sternberg CN, Chi KN, Olmos D, Sandhu S, Massard C et al..  2025.  Final Overall Survival and Molecular Data Associated with Clinical Outcomes in Patients Receiving Ipatasertib and Abiraterone in the Phase 3 IPATential150 Trial.. Eur Urol.
Rajendran S, Rehani E, Phu W, Zhan Q, Malmsten JE, Meseguer M, Miller KA, Rosenwaks Z, Elemento O, Zaninovic N et al..  2025.  A foundational model for in vitro fertilization trained on 18 million time-lapse images.. Nat Commun. 16(1):6235.
Claridge SE, Nath S, Baum A, Farias R, Cavallo J-A, Rizvi NM, De Boni L, Park E, Granados GLara, Hauesgen M et al..  2025.  Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.. Clin Transl Med. 15(2):e70078.
Umesh A, Cordogan S, Simpson SK, Bram JT, Jones RH, Schairer WW, Sboner A, Elemento O, Green DW, Fabricant PD.  2025.  Genetic Variants Related to TGF-β Signaling Pathway Modulate Risk of Meniscus Injury: A Multiancestry Genome-wide Association Study.. Clin Orthop Relat Res.
Borea R, Reduzzi C.  2025.  The growing field of liquid biopsy and its Snowball effect on reshaping cancer management.. J Liq Biopsy. 8:100293.
Petroni G, Galassi C, Gouin KH, Chen H-H, Buqué A, Bloy N, Yamazaki T, Sato A, Beltrán-Visiedo M, Campia G et al..  2025.  IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR+HER2- breast cancer via CX3CR1+ macrophages.. Nat Cancer.
Hissong E, Bhinder B, Kim J, Ohara K, Ravichandran H, Assaad MAl, Elsoukkary S, Shusterman M, Khan U, Eng KWha et al..  2025.  Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival.. Pathol Res Pract. 273:156150.
Mizuno K, Ku S-Y, Venkadakrishnan VBalaji, Bakht MK, Sigouros M, Chan J, Trigos A, Driskill JH, Manohar J, King A et al..  2025.  Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer.. Nat Commun. 16(1):5543.
Barton BM, Son F, Verma A, Bal SKumar, Tang Q, Wang R, Umphred-Wilson K, Khan R, Trichka J, Dong H et al..  2025.  IRE1α-XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs.. Nat Immunol.
Rowdo FPMadorsky, Martini R, Ackermann SE, Tang CP, Tranquille M, Irizarry A, Us I, Alawa O, Moyer JE, Sigouros M et al..  2025.  Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.. Cancer Res. 85(3):551-566.
Schiavone MLuisa, Scarpitta R, Ravera F, Bleve S, Reduzzi C, Di Cocco F, Dameri M, Zoppoli G, Naccarato AGiuseppe, Nuzzo PVitale et al..  2025.  Liquid biopsy in breast cancer: Redefining precision medicine.. J Liq Biopsy. 9:100312.
He Y, Waltman P, Kane T, Sigouros M, Chandra P, Gorski K, Zhang C, Proietti A, Singh A, Mittal V et al..  2025.  Longitudinal genomic analysis of five cases of recurrent thymomas.. J Thorac Oncol.
Howlader MJ, Rashighi M, Santambrogio L, Lu TT.  2025.  Lymphatic messengers: Non-antigen soluble mediators from diseased tissues to draining lymph nodes.. Curr Opin Immunol. 93:102536.
Albayram M, Richmond SB, Yagmurlu K, Tuna IS, Karakaya E, Ravichandran H, Tufan F, Lesha E, Mut M, Bunyak F et al..  2025.  Meningeal lymphatic architecture and drainage dynamics surrounding the human middle meningeal artery.. iScience. 28(11):113693.
Guevara D, Shin N, Boiko A, Valiev I, Elsaeed AG, Mosquera JMiguel, Assaad MAl, Manohar J, Sigouros M, Zaichikova A et al..  2025.  Mesonephric Adenocarcinoma in a Young Male Patient.. Anticancer Res. 45(2):619-623.
Chen HJoyce, Gardner EE, Shah Y, Zhang K, Thakur A, Zhang C, Elemento O, Varmus H.  2025.  Metastatic small cell lung cancer arises from TP53/RB1-deficient and MYC overproduction hESC-derived PNECs.. Elife. 13
Tyrakis PA, Kampjut D, Steele GF, H Lindström JG, Chirnomas D, Hopkins BD, Goncalves MD, Mukherjee S, Cantley LC, Maddocks ODK.  2025.  Multi-node inhibition targeting mTORC1, mTORC2 and PI3Kα potently inhibits the PI3K/AKT/mTOR pathway in endometrial and breast cancer models.. Br J Cancer.
Kyei I, Bea VJ, Gyan KK, Adjei E, Stonaker B, Bekele M, Abebe E, Davis M, Boakye A, Boateng R et al..  2025.  Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS).. Ann Surg Oncol.