| Title | Dissecting bulk transcriptomes of diffuse large B cell lymphoma. |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | McNally DR, Elemento O, Melnick A |
| Journal | Cancer Cell |
| Volume | 39 |
| Issue | 10 |
| Pagination | 1305-1307 |
| Date Published | 2021 Oct 11 |
| ISSN | 1878-3686 |
| Keywords | Gene Expression Profiling, Genomics, Humans, Lymphoma, Large B-Cell, Diffuse, Prognosis, Transcriptome |
| Abstract | Diffuse large B cell lymphoma (DLBCL) is a markedly phenotypically heterogenous disease, frequently assessed using bulk genomic techniques that blur the intrinsic heterogeneity of each tumor. In this issue of Cancer Cell, Steen et al. have utilized a computational framework called EcoTyper to skillfully dissect bulk transcriptomic tumor profiles into different cell type components in an unsupervised manner. |
| DOI | 10.1016/j.ccell.2021.09.006 |
| Alternate Journal | Cancer Cell |
| PubMed ID | 34597590 |