Englander Institute for Precision Medicine
Found 877 results
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2023
González-Muñoz T, Di Giannatale A, García-Silva S, Santos V, Sánchez-Redondo S, Savini C, Graña-Castro O, Blanco-Aparicio C, Fischer S, De Wever O et al..  2023.  Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis.. Clin Cancer Res. 29(18):3744-3758.
Cappelli LVincenzo, Fiore D, Phillip JM, Yoffe L, Di Giacomo F, Chiu W, Hu Y, Kayembe C, Ginsberg M, Consolino L et al..  2023.  Endothelial cell-leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities.. Blood. 141(5):503-518.
Galassi C, Galluzzi L.  2023.  Epigenetic escape of immunosurveillance by malignant cell precursors.. EMBO J. 42(10):e114050.
Cheong J-G, Ravishankar A, Sharma S, Parkhurst CN, Grassmann SA, Wingert CK, Laurent P, Ma S, Paddock L, Miranda IC et al..  2023.  Epigenetic memory of coronavirus infection in innate immune cells and their progenitors.. Cell. 186(18):3882-3902.e24.
Lin T-Y, Ramsamooj S, Perrier T, Liberatore K, Lantier L, Vasan N, Karukurichi K, Hwang S-K, Kesicki EA, Kastenhuber ER et al..  2023.  Epinephrine inhibits PI3Kα via the Hippo kinases.. Cell Rep. 42(12):113535.
Li D, Zhan Y, Wang N, Tang F, Lee CJ, Bayshtok G, Moore AR, Wong EWP, Pachai MR, Xie Y et al..  2023.  ETV4 mediates dosage-dependent prostate tumor initiation and cooperates with p53 loss to generate prostate cancer.. Sci Adv. 9(14):eadc9446.
Khani F, Hooper WF, Wang X, Chu TR, Shah M, Winterkorn L, Sigouros M, Conteduca V, Pisapia D, Wobker S et al..  2023.  Evolution of structural rearrangements in prostate cancer intracranial metastases.. NPJ Precis Oncol. 7(1):91.
Halabi S, Yang Q, Roy A, Luo B, Araujo JC, Logothetis C, Sternberg CN, Armstrong AJ, Carducci MA, Chi KN et al..  2023.  External Validation of a Prognostic Model of Overall Survival in Men With Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer.. J Clin Oncol. 41(15):2736-2746.
Chen HJoyce, Gardner EE, Shah Y, Zhang K, Thakur A, Zhang C, Elemento O, Varmus H.  2023.  FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS.. bioRxiv.
Sternberg CN, Petrylak DP, Bellmunt J, Nishiyama H, Necchi A, Gurney H, Lee J-L, van der Heijden MS, Rosenbaum E, Penel N et al..  2023.  FORT-1: Phase II/III Study of Rogaratinib Versus Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma Selected Based on / mRNA Expression.. J Clin Oncol. 41(3):629-639.
Ladewig MS, Jacobsen JOB, Wagner AH, Danis D, Kassaby BEl, Gargano M, Groza T, Baudis M, Steinhaus R, Seelow D et al..  2023.  GA4GH Phenopackets: A Practical Introduction.. Adv Genet (Hoboken). 4(1):2200016.
Weinstock JS, Laurie CA, Broome JG, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Lewis JP, Boerwinkle E, Barnes KC et al..  2023.  The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.. Sci Adv. 9(17):eabm4945.
Kulm S, Kaidi AC, Kolin D, Langhans MT, Bostrom MP, Elemento O, Shen TS.  2023.  Genetic Risk Factors for End-Stage Hip Osteoarthritis Treated With Total Hip Arthroplasty: A Genome-wide Association Study.. J Arthroplasty.
Chukwu W, Lee S, Crane A, Zhang S, Mittra I, Imielinski M, Beroukhim R, Dubois F, Dalin S.  2023.  Genomic sequence context differs between germline and somatic structural variants allowing for their differentiation in tumor samples without paired normals.. bioRxiv.
Jessurun J, Orr C, McNulty SN, Hagen CE, Alnajar H, Wilkes D, Kudman S, Assaad MAl, Dorsaint P, Ohara K et al..  2023.  GLI1 -Rearranged Enteric Tumor : Expanding the Spectrum of Gastrointestinal Neoplasms With GLI1 Gene Fusions.. Am J Surg Pathol. 47(1):65-73.
Dhital B, Santasusagna S, Kirthika P, Xu M, Li P, Carceles-Cordon M, Soni RK, Li Z, Hendrickson RC, Schiewer MJ et al..  2023.  Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer.. Cell Rep Med. 4(2):100937.
Van Emmenis L, Ku S-Y, Gayvert K, Branch JR, Brady NJ, Basu S, Russell M, Cyrta J, Vosoughi A, Sailer V et al..  2023.  The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer.. Cancer Res Commun. 3(8):1447-1459.
Bovonratwet P, Kulm S, Kolin DA, Song J, Morse KW, Cunningham ME, Albert TJ, Sandhu HS, Kim HJo, Iyer S et al..  2023.  Identification of Novel Genetic Markers for the Risk of Spinal Pathologies: A Genome-Wide Association Study of 2 Biobanks.. J Bone Joint Surg Am.
Galluzzi L, Kepp O, Hett E, Kroemer G, Marincola FM.  2023.  Immunogenic cell death in cancer: concept and therapeutic implications.. J Transl Med. 21(1):162.
Galassi C, Klapp V, Formenti SC, Demaria S, Galluzzi L.  2023.  Immunologically relevant effects of radiation therapy on the tumor microenvironment.. Essays Biochem.
Necchi A, Faltas BM, Slovin SF, Meeks JJ, Pal SK, Schwartz LH, Huang RSP, Li R, Manley B, Chahoud J et al..  2023.  Immunotherapy in the Treatment of Localized Genitourinary Cancers.. JAMA Oncol. 9(10):1447-1454.
Assaad MAl, Gundem G, Liechty B, Sboner A, Medina J, Papaemmanuil E, Sternberg CN, Marks A, Souweidane MM, Greenfield JP et al..  2023.  The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.. Cold Spring Harb Mol Case Stud. 9(4)
Coppock JA, Zimmer NE, Englander ZA, Danyluk ST, Kosinski AS, Spritzer CE, Goode AP, DeFrate LE.  2023.  In vivo intervertebral disc mechanical deformation following a treadmill walking "stress test" is inversely related to T1rho relaxation time.. Osteoarthritis Cartilage. 31(1):126-133.
Noch EK, Palma LN, Yim I, Bullen N, Qiu Y, Ravichandran H, Kim J, Rendeiro A, Davis MB, Elemento O et al..  2023.  Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma.. Neuro Oncol. 25(12):2165-2176.
Holicek P, Fucikova J, Galluzzi L.  2023.  Interferon signaling restrains renal cell carcinoma heterogeneity.. Trends Cancer. 9(11):871-873.