| Title | MDSCs sneak CSCs out of (immuno)surveillance. |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Authors | Jiménez-Cortegana C, Galassi C, Galluzzi L |
| Journal | Trends Immunol |
| Volume | 43 |
| Issue | 1 |
| Pagination | 1-3 |
| Date Published | 2022 Jan |
| ISSN | 1471-4981 |
| Keywords | Aldehyde Dehydrogenase, Humans, Myeloid-Derived Suppressor Cells, Neoplasms, Neoplastic Stem Cells |
| Abstract | Cancer stem cells (CSCs) are known for their superior tumor-initiating and tumor-repopulating potential, partly reflecting their pronounced ability to evade immune recognition. Liu and colleagues recently identified a new aldehyde dehydrogenase (ALDH)-dependent mechanism whereby triple-negative breast CSCs evade immunosurveillance upon recruitment of myeloid-derived suppressor cells. |
| DOI | 10.1016/j.it.2021.11.008 |
| Alternate Journal | Trends Immunol |
| PubMed ID | 34863632 |