| Title | NK cells beat T cells at early breast cancer control. |
| Publication Type | Journal Article |
| Year of Publication | 2020 |
| Authors | Buqué A, Bloy N, Petroni G, Kroemer G, Galluzzi L |
| Journal | Oncoimmunology |
| Volume | 9 |
| Issue | 1 |
| Pagination | 1806010 |
| Date Published | 2020 Aug 23 |
| ISSN | 2162-4011 |
| Keywords | Animals, CD8-Positive T-Lymphocytes, Killer Cells, Natural, Mice, Neoplasms |
| Abstract | Cancer immunosurveillance generally relies on adaptive immune programs executed by CD8 T cells. Our findings demonstrate that CD8 T cells fail to control early oncogenesis in a mouse model of luminal B breast cancer and suggest that natural killer (NK) cells may instead play a predominant role in this setting. |
| DOI | 10.1080/2162402X.2020.1806010 |
| Alternate Journal | Oncoimmunology |
| PubMed ID | 32923169 |
| PubMed Central ID | PMC7458610 |