Englander Institute for Precision Medicine
Illustration of chromatin in the nucleus. Credit: Shutterstock.

A team co-led by researchers at Weill Cornell Medicine and the New York Genome Center has developed an advanced method for revealing how gene mutations disrupt the normal packaging of DNA. These structural changes, which alter patterns of gene activity in a cell, are known as epigenetic changes and can lead to malignancy.

The new method, described in a ...

Niroshana Anandasabapathy, M.D., Ph.D.,

Melanoma, the deadliest form of skin cancer, is on the rise. But there's a silver lining as this increase might be partly due to earlier detection. The use of Dermoscopy, a handheld device which allows closer surveillance of the organization of a mole or lesion, has greatly facilitated in detection of melanomas and moles that are dysplastic/or atypical. This device allows doctors to see the intricate structure of moles...

Pictured is a 3D illustration of single stranded RNA molecules. The atlas of RNA isoforms will serve as a basic reference for  studying normal and abnormal brain function and development. Credit: Shutterstock

Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA (mRNA) variants in the mouse and human brain. The atlas is an important new resource in understanding brain development, neuron specialization and other brain functions.

RNA transcripts that are copied from DNA sequences carry the instructions for...