Englander Institute for Precision Medicine
Found 797 results
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2021
Khosravi P, Lysandrou M, Eljalby M, Li Q, Kazemi E, Zisimopoulos P, Sigaras A, Brendel M, Barnes J, Ricketts C et al..  2021.  A Deep Learning Approach to Diagnostic Classification of Prostate Cancer Using Pathology-Radiology Fusion.. J Magn Reson Imaging. 54(2):462-471.
Xu Z, Verma A, Naveed U, Bakhoum SF, Khosravi P, Elemento O.  2021.  Deep learning predicts chromosomal instability from histopathology images.. iScience. 24(5):102394.
Cibula D, Rob L, Mallmann P, Knapp P, Klat J, Chovanec J, Minar L, Melichar B, Hein A, Kieszko D et al..  2021.  Dendritic cell-based immunotherapy (DCVAC/OvCa) combined with second-line chemotherapy in platinum-sensitive ovarian cancer (SOV02): A randomized, open-label, phase 2 trial.. Gynecol Oncol. 162(3):652-660.
Jordan ERose, Jahreiss L, Kasi PMurtaza.  2021.  Deploying an artificial intelligence-based online search tool to increase patients' access to and understanding of solid tumor gastrointestinal clinical trials.. J Gastrointest Oncol. 12(5):2045-2051.
Baggiolini A, Callahan SJ, Montal E, Weiss JM, Trieu T, Tagore MM, Tischfield SE, Walsh RM, Suresh S, Fan Y et al..  2021.  Developmental chromatin programs determine oncogenic competence in melanoma.. Science. 373(6559):eabc1048.
Cox N, Crozet L, Holtman IR, Loyher P-L, Lazarov T, White JB, Mass E, E Stanley R, Elemento O, Glass CK et al..  2021.  Diet-regulated production of PDGFcc by macrophages controls energy storage.. Science. 373(6550)
Taza F, Holler AE, Fu W, Wang H, Adra N, Albany C, Ashkar R, Cheng HH, Sokolova AO, Agarwal N et al..  2021.  Differential Activity of PARP Inhibitors in - Versus -Altered Metastatic Castration-Resistant Prostate Cancer.. JCO Precis Oncol. 5
Pan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AMaria, Fischer K, Zhang C, Betel D et al..  2021.  Discovery of Candidate DNA Methylation Cancer Driver Genes.. Cancer Discov. 11(9):2266-2281.
McNally DR, Elemento O, Melnick A.  2021.  Dissecting bulk transcriptomes of diffuse large B cell lymphoma.. Cancer Cell. 39(10):1305-1307.
Jorgez CJ, Seth A, Wilken N, Bournat JC, Chen CH, Lamb DJ.  2021.  E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling.. Development. 148(1)
Sternberg CN, Castellano D, de Bono J, Fizazi K, Tombal B, Wülfing C, Kramer G, Eymard J-C, Bamias A, Carles J et al..  2021.  Efficacy and Safety of Cabazitaxel Versus Abiraterone or Enzalutamide in Older Patients with Metastatic Castration-resistant Prostate Cancer in the CARD Study.. Eur Urol. 80(4):497-506.
Wong RL, Ferris LA, Do OA, Holt SK, Ramos JD, Crabb SJ, Sternberg CN, Bellmunt J, Ladoire S, De Giorgi U et al..  2021.  Efficacy of Platinum Rechallenge in Metastatic Urothelial Carcinoma After Previous Platinum-Based Chemotherapy for Metastatic Disease.. Oncologist. 26(12):1026-1034.
Montrose DC, Saha S, Foronda M, McNally EM, Chen J, Zhou XKathy, Ha T, Krumsiek J, Buyukozkan M, Verma A et al..  2021.  Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil.. Cancer Res. 81(9):2275-2288.
Fedrizzi T, Ciani Y, Lorenzin F, Cantore T, Gasperini P, Demichelis F.  2021.  Fast mutual exclusivity algorithm nominates potential synthetic lethal gene pairs through brute force matrix product computations.. Comput Struct Biotechnol J. 19:4394-4403.
Aeppli S, Schmaus M, Eisen T, Escudier B, Grünwald V, Larkin J, McDermott D, Oldenburg J, Porta C, Rini BI et al..  2021.  First-line treatment of metastatic clear cell renal cell carcinoma: a decision-making analysis among experts.. ESMO Open. 6(1):100030.
Shohdy KS, Bareja R, Sigouros M, Wilkes DC, Dorsaint P, Manohar J, Bockelman D, Xiang JZ, Kim R, Ohara K et al..  2021.  Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors.. NPJ Genom Med. 6(1):66.
Mukhopadhyay C, Yang C, Xu L, Liu D, Wang Y, Huang D, Deonarine LDayal, Cyrta J, Davicioni E, Sboner A et al..  2021.  G3BP1 inhibits Cul3 to amplify AR signaling and promote prostate cancer.. Nat Commun. 12(1):6662.
Wolujewicz P, Aguiar-Pulido V, AbdelAleem A, Nair V, Thareja G, Suhre K, Shaw GM, Finnell RH, Elemento O, M Ross E.  2021.  Genome-wide investigation identifies a rare copy-number variant burden associated with human spina bifida.. Genet Med. 23(7):1211-1218.
Merseburger AS, Waldron N, Ribal MJ, Heidenreich A, Perner S, Fizazi K, Sternberg CN, Mateo J, Wirth MP, Castro E et al..  2021.  Genomic Testing in Patients with Metastatic Castration-resistant Prostate Cancer: A Pragmatic Guide for Clinicians.. Eur Urol. 79(4):519-529.
Davis MB.  2021.  Genomics and Cancer Disparities: The Justice and Power of Inclusion.. Cancer Discov. 11(4):805-809.
Suhre K, Sarwath H, Engelke R, Sohail MUmar, Cho SJung, Whalen W, Alvarez-Mulett S, Krumsiek J, Choi AMK, Schmidt F.  2021.  Identification of Robust Protein Associations With COVID-19 Disease Based on Five Clinical Studies.. Front Immunol. 12:781100.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S et al..  2021.  Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.. Nature. 589(7841):270-275.
Moslehi J, Lichtman AH, Sharpe AH, Galluzzi L, Kitsis RN.  2021.  Immune checkpoint inhibitor-associated myocarditis: manifestations and mechanisms.. J Clin Invest. 131(5)
Fornarini G, Rebuzzi SE, Banna GL, Calabrò F, Scandurra G, De Giorgi U, Masini C, Baldessari C, Naglieri E, Caserta C et al..  2021.  Immune-inflammatory biomarkers as prognostic factors for immunotherapy in pretreated advanced urinary tract cancer patients: an analysis of the Italian SAUL cohort.. ESMO Open. 6(3):100118.
Sato A, Buqué A, Yamazaki T, Bloy N, Petroni G, Galluzzi L.  2021.  Immunofluorescence microscopy-based assessment of cytosolic DNA accumulation in mammalian cells.. STAR Protoc. 2(2):100488.