Englander Institute for Precision Medicine
Found 797 results
Author Title Type [ Year(Desc)]
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2021
Bloehdorn J, Braun A, Taylor-Weiner A, Jebaraj BMichael Ch, Robrecht S, Krzykalla J, Pan H, Giza A, Akylzhanova G, Holzmann K et al..  2021.  Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.. Nat Commun. 12(1):5395.
Persi E, Wolf YI, Horn D, Ruppin E, Demichelis F, Gatenby RA, Gillies RJ, Koonin EV.  2021.  Mutation-selection balance and compensatory mechanisms in tumour evolution.. Nat Rev Genet. 22(4):251-262.
Morciano G, Pedriali G, Bonora M, Pavasini R, Mikus E, Calvi S, Bovolenta M, Lebiedzinska-Arciszewska M, Pinotti M, Albertini A et al..  2021.  A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients.. Cell Rep. 35(2):108983.
Nilsson-Payant BE, Uhl S, Grimont A, Doane AS, Cohen P, Patel RS, Higgins CA, Acklin JA, Bram Y, Chandar V et al..  2021.  The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication.. J Virol. 95(23):e0125721.
Doane AS, Chu C-S, Di Giammartino DCampigli, Rivas MA, Hellmuth JC, Jiang Y, Yusufova N, Alonso A, Roeder RG, Apostolou E et al..  2021.  OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity.. Nat Immunol. 22(10):1327-1340.
M Calvo-Vidal N, Zamponi N, Krumsiek J, Stockslager MA, Revuelta MV, Phillip JM, Marullo R, Tikhonova E, Kotlov N, Patel J et al..  2021.  Oncogenic HSP90 Facilitates Metabolic Alterations in Aggressive B-cell Lymphomas.. Cancer Res. 81(20):5202-5216.
Che M, Chaturvedi A, Munro SA, Pitzen SP, Ling A, Zhang W, Mentzer J, Ku S-Y, Puca L, Zhu Y et al..  2021.  Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer.. Nat Commun. 12(1):6377.
Shah Y, Verma A, Marderstein AR, White J, Bhinder B, J Medina SGarcia, Elemento O.  2021.  Pan-cancer analysis reveals molecular patterns associated with age.. Cell Rep. 37(10):110100.
Thorand B, Zierer A, Buyukozkan M, Krumsiek J, Bauer A, Schederecker F, Sudduth-Klinger J, Meisinger C, Grallert H, Rathmann W et al..  2021.  A Panel of 6 Biomarkers Significantly Improves the Prediction of Type 2 Diabetes in the MONICA/KORA Study Population.. J Clin Endocrinol Metab. 106(4):e1647-e1659.
Karkampouna S, La Manna F, Benjak A, Kiener M, De Menna M, Zoni E, Grosjean J, Klima I, Garofoli A, Bolis M et al..  2021.  Patient-derived xenografts and organoids model therapy response in prostate cancer.. Nat Commun. 12(1):1117.
Jayaram A, Wingate A, Wetterskog D, Wheeler G, Sternberg CN, Jones R, Berruti A, Lefresne F, Lahaye M, Thomas S et al..  2021.  Plasma tumor gene conversions after one cycle abiraterone acetate for metastatic castration-resistant prostate cancer: a biomarker analysis of a multicenter international trial.. Ann Oncol. 32(6):726-735.
Clement CC, Nanaware PP, Yamazaki T, Negroni MPia, Ramesh K, Morozova K, Thangaswamy S, Graves A, Kim HJung, Li TWanxia et al..  2021.  Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery.. Immunity. 54(4):721-736.e10.
Marderstein AR, Kulm S, Peng C, Tamimi R, Clark AG, Elemento O.  2021.  A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk.. Am J Hum Genet. 108(9):1752-1764.
Buqué A, Bloy N, Kroemer G, Galluzzi L.  2021.  Possible mechanisms of cancer prevention by nicotinamide.. Br J Pharmacol. 178(10):2034-2040.
Gillessen S, Sauvé N, Collette L, Daugaard G, de Wit R, Albany C, Tryakin A, Fizazi K, Stahl O, Gietema JA et al..  2021.  Predicting Outcomes in Men With Metastatic Nonseminomatous Germ Cell Tumors (NSGCT): Results From the IGCCCG Update Consortium.. J Clin Oncol. 39(14):1563-1574.
Kolin DA, Kulm S, Elemento O.  2021.  Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank.. Sci Rep. 11(1):21340.
Rendeiro AF, Casano J, Vorkas CKyriakos, Singh H, Morales A, DeSimone RA, Ellsworth GB, Soave R, Kapadia SN, Saito K et al..  2021.  Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression.. Life Sci Alliance. 4(2)
Clement CC, Nanaware PP, Stern LJ, Santambrogio L.  2021.  A protocol for qualitative and quantitative measurement of endosomal processing using hot spot analysis.. STAR Protoc. 2(3):100648.
Dixon G, Pan H, Yang D, Rosen BP, Jashari T, Verma N, Pulecio J, Caspi I, Lee K, Stransky S et al..  2021.  QSER1 protects DNA methylation valleys from de novo methylation.. Science. 372(6538)
Petroni G, Buqué A, Yamazaki T, Bloy N, Di Liberto M, Chen-Kiang S, Formenti SC, Galluzzi L.  2021.  Radiotherapy Delivered before CDK4/6 Inhibitors Mediates Superior Therapeutic Effects in ER Breast Cancer.. Clin Cancer Res. 27(7):1855-1863.
Lhuillier C, Rudqvist N-P, Yamazaki T, Zhang T, Charpentier M, Galluzzi L, Dephoure N, Clement CC, Santambrogio L, Zhou XKathy et al..  2021.  Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control.. J Clin Invest. 131(5)
Grbesa I, Augello MA, Liu D, McNally DR, Gaffney CD, Huang D, Lin K, Ivenitsky D, Goueli R, Robinson BD et al..  2021.  Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.. Cell Rep. 36(10):109625.
Loehr A, Patnaik A, Campbell D, Shapiro J, Bryce AH, McDermott R, Sautois B, Vogelzang NJ, Bambury RM, Voog E et al..  2021.  Response to Rucaparib in BRCA-Mutant Metastatic Castration-Resistant Prostate Cancer Identified by Genomic Testing in the TRITON2 Study.. Clin Cancer Res. 27(24):6677-6686.
Kassambara A, Herviou L, Ovejero S, Jourdan M, Thibaut C, Vikova V, Pasero P, Elemento O, Moreaux J.  2021.  RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.. Leukemia. 35(5):1451-1462.
Alaterre E, Vikova V, Kassambara A, Bruyer A, Robert N, Requirand G, Bret C, Herbaux C, Vincent L, Cartron G et al..  2021.  RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma.. J Pers Med. 11(10)