Englander Institute for Precision Medicine
Found 811 results
Author Title Type [ Year(Asc)]
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2025
Barton BM, Son F, Verma A, Bal SKumar, Tang Q, Wang R, Umphred-Wilson K, Khan R, Trichka J, Dong H et al..  2025.  IRE1α-XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs.. Nat Immunol.
Rowdo FPMadorsky, Martini R, Ackermann SE, Tang CP, Tranquille M, Irizarry A, Us I, Alawa O, Moyer JE, Sigouros M et al..  2025.  Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.. Cancer Res. 85(3):551-566.
Howlader MJ, Rashighi M, Santambrogio L, Lu TT.  2025.  Lymphatic messengers: Non-antigen soluble mediators from diseased tissues to draining lymph nodes.. Curr Opin Immunol. 93:102536.
Guevara D, Shin N, Boiko A, Valiev I, Elsaeed AG, Mosquera JMiguel, Assaad MAl, Manohar J, Sigouros M, Zaichikova A et al..  2025.  Mesonephric Adenocarcinoma in a Young Male Patient.. Anticancer Res. 45(2):619-623.
Tyrakis PA, Kampjut D, Steele GF, H Lindström JG, Chirnomas D, Hopkins BD, Goncalves MD, Mukherjee S, Cantley LC, Maddocks ODK.  2025.  Multi-node inhibition targeting mTORC1, mTORC2 and PI3Kα potently inhibits the PI3K/AKT/mTOR pathway in endometrial and breast cancer models.. Br J Cancer.
Fiore D, Cappelli LVincenzo, Zhaoqi L, Kotlov N, Sorokina M, Phillip J, Zumbo P, Yoffe L, Ghione P, Wang A et al..  2025.  A patient-derived T cell lymphoma biorepository uncovers pathogenetic mechanisms and host-related therapeutic vulnerabilities.. Cell Rep Med. :102029.
Horne CR, Dite TA, Young SN, Mather LJ, Dagley LF, Johnson JL, Yaron-Barir TM, Huntsman EM, Daly LA, Byrne DP et al..  2025.  "PSKH1 kinase activity is differentially modulated via allosteric binding of Ca²⁺ sensor proteins". Proc Natl Acad Sci U S A. 122(8):e2420961122.
Laurent P-A, Andre F, Bobard A, Deandreis D, Demaria S, Depil S, Eichmüller SB, Fernandez-Palomo C, Foijer F, Galluzzi L et al..  2025.  Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7th immunorad conference.. Oncoimmunology. 14(1):2432726.
Nagar H, Diven MA, Rippon B, Barbieri CE, Hu JC, Scherr DS, Yadav P, Tshering L, Chandrasekhar S, Wolfe S et al..  2025.  A Randomized Controlled Phase 2 Trial Comparing Salvage Radiotherapy for Prostate Cancer Delivered in 4 Versus 2 Weeks (SHORTER): Acute Genitourinary and Gastrointestinal Patient-reported Outcomes at a Single Institution.. Eur Urol Oncol.
Chukwu W, Lee S, Crane A, Zhang S, Webster S, Dakhama O, Mittra I, Rauert C, Imielinski M, Beroukhim R et al..  2025.  A sequence context-based approach for classifying tumor structural variants without paired normal samples.. Cell Rep Methods. :100991.
Kim J, Ravichandran H, Yoffe L, Bhinder B, Finos K, Singh A, Pua BB, Bates S, Huang BEmma, Rendeiro AF et al..  2025.  Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression.. bioRxiv.
Lv W, Zeng Y, Li C, Liang Y, Tao H, Zhu Y, Sui X, Li Y, Jiang S, Gao Q et al..  2025.  Spatial-Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment.. Cancer Discov. :OF1-OF22.
Al-Thani NM, Zaghlool SB, Toor SM, Abou-Samra ABadi, Suhre K, Albagha OME.  2025.  Subtyping of Type 2 Diabetes from a Large Middle Eastern Biobank: Implications for Precision Medicine.. Mol Metab. :102195.
Rubinelli L, Manzo OLaura, Sungho J, Del Gaudio I, Bareja R, Marino A, Palikhe S, Di Mauro V, Bucci M, Falcone DJ et al..  2025.  Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases.. Nat Commun. 16(1):1968.
Yost KE, Zhao Y, Hung KL, Zhu K, Xu D, M Corces R, Shams S, Louie BH, Sarmashghi S, Sundaram L et al..  2025.  Three-dimensional genome landscape of primary human cancers.. Nat Genet. 57(5):1189-1200.
Breves SL, Di Giammartino DCampigli, Nicholson J, Cirigliano S, Mahmood SRaza, Lee UJin, Martinez-Fundichely A, Jungverdorben J, Singhania R, Rajkumar S et al..  2025.  Three-dimensional regulatory hubs support oncogenic programs in glioblastoma.. Mol Cell.
Honigsberg R, Cruz T, Yoffe L, Tang MStephanie, Dicle O, Markowitz G, Michael M, Singh A, Altorki NK, Elemento O et al..  2025.  Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade.. bioRxiv.
Guevara D, Shin N, Boiko A, Valiev I, Elsaeed AG, Mosquera JMiguel, Assaad MAl, Manohar J, Sigouros M, Zaichikova A et al..  2025.  Unusual Presentation of Advanced Urothelial Cancer in a Young Patient.. Anticancer Res. 45(2):613-618.
Bonacci RE, McGill M, Le NThuy Anh, Barkarar M, Finnegan C, Wilson M, Ajagbe O, Udekwu CC, Gorski K, Manohar J et al..  2025.  Upregulation of the interferon-inducible antiviral gene RSAD2 in neuroendocrine prostate cancer via PVT1 exon 9 dependent and independent pathways.. J Biol Chem. :108370.
2024
Guillet S, Lazarov T, Jordan N, Boisson B, Tello M, Craddock B, Zhou T, Nishi C, Bareja R, Yang H et al..  2024.  ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.. Elife. 13
Lira MCecilia, Vanpouille-Box C, Galluzzi L.  2024.  Adaptive inhibition of CGAS signaling by TREX1.. Trends Cancer. 10(3):177-179.
San Pedro JManuel Bra, Aranda F, Buqué A, Galluzzi L.  2024.  Animal models of disease: Achievements and challenges.. Methods Cell Biol. 188:xv-xxi.
Stenzl A, Armstrong AJ, Sboner A, Ghith J, Serfass L, Bland CS, Schijvenaars BJA, Sternberg CN.  2024.  Artificial INtelligence to Support Informed DEcision-making (INSIDE) for Improved Literature Analysis in Oncology.. Eur Urol Focus.
Desai P, Zhou Y, Grenet J, Handelman SK, Crispino CM, Tarbay LN, Whitsel EA, Roboz G, Barac A, Honigberg M et al..  2024.  Association of clonal hematopoiesis and mosaic chromosomal alterations with solid malignancy incidence and mortality.. Cancer.
De Martino M, Rathmell JC, Galluzzi L, Vanpouille-Box C.  2024.  Author Correction: Cancer cell metabolism and antitumour immunity.. Nat Rev Immunol.