Englander Institute for Precision Medicine
Found 877 results
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2020
Liu H, Paddock MN, Wang H, Murphy CJ, Geck RC, Navarro AJ, Wulf GM, Elemento O, Haucke V, Cantley LC et al..  2020.  The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer.. Cancer Discov. 10(8):1226-1239.
Liu D, Shoag JE, Poliak D, Goueli RS, Ravikumar V, Redmond D, Vosoughi A, Fontugne J, Pan H, Lee D et al..  2020.  Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes.. Nat Commun. 11(1):1987.
Han T, Goswami S, Hu Y, Tang F, Zafra MPaz, Murphy C, Cao Z, Poirier JT, Khurana E, Elemento O et al..  2020.  Lineage Reversion Drives WNT Independence in Intestinal Cancer.. Cancer Discov. 10(10):1590-1609.
Rendeiro AF, Casano J, Vorkas CKyriakos, Singh H, Morales A, DeSimone RA, Ellsworth GB, Soave R, Kapadia SN, Saito K et al..  2020.  Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression.. medRxiv.
Xu D, Gokcumen O, Khurana E.  2020.  Loss-of-function tolerance of enhancers in the human genome.. PLoS Genet. 16(4):e1008663.
Hensler M, Kasikova L, Fiser K, Rakova J, Skapa P, Laco J, Lanickova T, Pecen L, Truxova I, Vosahlikova S et al..  2020.  M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer.. J Immunother Cancer. 8(2)
Gilvary C, Elkhader J, Madhukar N, Henchcliffe C, Goncalves MD, Elemento O.  2020.  A machine learning and network framework to discover new indications for small molecules.. PLoS Comput Biol. 16(8):e1008098.
Punjani N, Lamb DJ.  2020.  Male infertility and genitourinary birth defects: there is more than meets the eye.. Fertil Steril. 114(2):209-218.
Gillessen S, Attard G, Beer TM, Beltran H, Bjartell A, Bossi A, Briganti A, Bristow RG, Chi KN, Clarke N et al..  2020.  Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019.. Eur Urol. 77(4):508-547.
Ricketts C, Seidman D, Popic V, Hormozdiari F, Batzoglou S, Hajirasouliha I.  2020.  Meltos: multi-sample tumor phylogeny reconstruction for structural variants.. Bioinformatics. 36(4):1082-1090.
Yamazaki T, Galluzzi L.  2020.  Mitochondrial control of innate immune signaling by irradiated cancer cells.. Oncoimmunology. 9(1):1797292.
Yamazaki T, Kirchmair A, Sato A, Buqué A, Rybstein M, Petroni G, Bloy N, Finotello F, Stafford L, Manzano ENavarro et al..  2020.  Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy.. Nat Immunol. 21(10):1160-1171.
Hassler MR, Bray F, Catto JWF, Grollman AP, Hartmann A, Margulis V, Matin SF, Roupret M, Sfakianos JP, Shariat SF et al..  2020.  Molecular Characterization of Upper Tract Urothelial Carcinoma in the Era of Next-generation Sequencing: A Systematic Review of the Current Literature.. Eur Urol. 78(2):209-220.
Matrai C, Motanagh S, Mirabelli S, Ma L, He B, Chapman-Davis E, Kurtis B, Elemento O, Mosquera JMiguel, Ellenson LH.  2020.  Molecular Profiles of Mixed Endometrial Carcinoma.. Am J Surg Pathol. 44(8):1104-1111.
Shah MA, Enzinger P, Ko AH, Ocean AJ, Philip PAgop, Thakkar PV, Cleveland K, Lu Y, Kortmansky J, Christos PJ et al..  2020.  Multicenter Phase II Study of Cabazitaxel in Advanced Gastroesophageal Cancer: Association of HER2 Expression and M2-Like Tumor-Associated Macrophages with Patient Outcome.. Clin Cancer Res. 26(18):4756-4766.
Melis M, Zhang T, Scognamiglio T, Gudas LJ.  2020.  Mutations in long-lived epithelial stem cells and their clonal progeny in pre-malignant lesions and in oral squamous cell carcinoma.. Carcinogenesis. 41(11):1553-1564.
Fulmer CG, Park K, Dilcher T, Ho M, Mirabelli S, Alperstein S, Hissong EM, Pittman M, Siddiqui M, Heymann JJ et al..  2020.  Next-generation sequencing of residual cytologic fixative preserved DNA from pancreatic lesions: A pilot study.. Cancer Cytopathol. 128(11):840-851.
Buqué A, Bloy N, Petroni G, Kroemer G, Galluzzi L.  2020.  NK cells beat T cells at early breast cancer control.. Oncoimmunology. 9(1):1806010.
Chong SJun Fei, Marchi S, Petroni G, Kroemer G, Galluzzi L, Pervaiz S.  2020.  Noncanonical Cell Fate Regulation by Bcl-2 Proteins.. Trends Cell Biol. 30(7):537-555.
Fragliasso V, Verma A, Manzotti G, Tameni A, Bareja R, Heavican TB, Iqbal J, Wang R, Fiore D, Mularoni V et al..  2020.  The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK anaplastic large cell lymphoma by regulating the DNA helicase HELLS.. Leukemia. 34(11):2964-2980.
Kumar S, Warrell J, Li S, McGillivray PD, Meyerson W, Salichos L, Harmanci A, Martinez-Fundichely A, W Y Chan C, Nielsen MMuhlig et al..  2020.  Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences.. Cell. 180(5):915-927.e16.
Park K, Tran H, Eng KW, Ramazanoglu S, Rolon RMMarrero, Scognamiglio T, Borczuk A, Mosquera JMiguel, Pan Q, Sboner A et al..  2020.  Performance Characteristics of a Targeted Sequencing Platform for Simultaneous Detection of Single Nucleotide Variants, Insertions/Deletions, Copy Number Alterations, and Gene Fusions in Cancer Genome.. Arch Pathol Lab Med. 144(12):1535-1546.
Mondanelli G, Coletti A, Greco FAntonio, Pallotta MTeresa, Orabona C, Iacono A, Belladonna MLaura, Albini E, Panfili E, Fallarino F et al..  2020.  Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.. Proc Natl Acad Sci U S A. 117(7):3848-3857.
Heymann JJ, Yoxtheimer LM, Park HJin, Fernandez EM, Facey KE, Alperstein SA, Tran HV, Baek I, Scognamiglio T, Rennert H et al..  2020.  Preanalytic variables in quality and quantity of nucleic acids extracted from FNA specimens of thyroid gland nodules collected in CytoLyt: Cellularity and storage time.. Cancer Cytopathol. 128(9):656-672.
Hajirasouliha I, Elemento O.  2020.  Precision medicine and artificial intelligence: overview and relevance to reproductive medicine.. Fertil Steril. 114(5):908-913.