Englander Institute for Precision Medicine

Publications

Found 844 results

Author Title Type [ Year

]

2025

Bhinder B, Friedl V, Sethuraman S, Risso D, Chiotti KE, R Mashl J, Ellrott KP, Lee JA, Wong CK, Gyan K et al.. 2025. Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles.. Sci Rep. 15(1):23921.

Fiore D, Cappelli LVincenzo, Zhaoqi L, Kotlov N, Sorokina M, Phillip J, Zumbo P, Yoffe L, Ghione P, Wang A et al.. 2025. A patient-derived T cell lymphoma biorepository uncovers pathogenetic mechanisms and host-related therapeutic vulnerabilities.. Cell Rep Med. :102029.

K Devi SP, Wang E, Jaiswal A, Konieczny P, Kim T-G, Nirschl CJ, Verma A, Liu Y, Milczanowski J, Christo SN et al.. 2025. PD-1 is requisite for skin TRM cell formation and specification by TGFβ.. Nat Immunol. 26(8):1339-1351.

Horne CR, Dite TA, Young SN, Mather LJ, Dagley LF, Johnson JL, Yaron-Barir TM, Huntsman EM, Daly LA, Byrne DP et al.. 2025. "PSKH1 kinase activity is differentially modulated via allosteric binding of Ca²⁺ sensor proteins". Proc Natl Acad Sci U S A. 122(8):e2420961122.

Müller-Dott S, Jaehnig EJ, Munchic KPham, Jiang W, Yaron-Barir TM, Savage SR, Garrido-Rodriguez M, Johnson JL, Lussana A, Petsalaki E et al.. 2025. Publisher Correction: Comprehensive evaluation of phosphoproteomic-based kinase activity inference.. Nat Commun. 16(1):6591.

Laurent P-A, Andre F, Bobard A, Deandreis D, Demaria S, Depil S, Eichmüller SB, Fernandez-Palomo C, Foijer F, Galluzzi L et al.. 2025. Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7th immunorad conference.. Oncoimmunology. 14(1):2432726.

Nagar H, Diven MA, Rippon B, Barbieri CE, Hu JC, Scherr DS, Yadav P, Tshering L, Chandrasekhar S, Wolfe S et al.. 2025. A Randomized Controlled Phase 2 Trial Comparing Salvage Radiotherapy for Prostate Cancer Delivered in 4 Versus 2 Weeks (SHORTER): Acute Genitourinary and Gastrointestinal Patient-reported Outcomes at a Single Institution.. Eur Urol Oncol.

Akinsanya K, AlQuraishi M, Boija A, Chodera J, Cichońska A, Ghassemi M, Head M, Jin W, Kibbe WA, Krogan N et al.. 2025. Redefining druggable targets with artificial intelligence.. Nat Biotechnol.

Gilani A, Stein BD, Hoffmann A, de Lima RPereira, Ha EE, Homan EA, Ma L, Rubio-Navarro A, Wun TTha Ra, Carrascal GJose Ayala et al.. 2025. Secretory kinase FAM20C triggers adipocyte dysfunction inciting insulin resistance and inflammation in obesity.. J Clin Invest.

Chukwu W, Lee S, Crane A, Zhang S, Webster S, Dakhama O, Mittra I, Rauert C, Imielinski M, Beroukhim R et al.. 2025. A sequence context-based approach for classifying tumor structural variants without paired normal samples.. Cell Rep Methods. :100991.

Kim J, Ravichandran H, Yoffe L, Bhinder B, Finos K, Singh A, Pua BB, Bates S, Huang BEmma, Rendeiro AF et al.. 2025. Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression.. bioRxiv.

Lakin KS, Spivack J, Gordon JK, Zhang Y, Jannat-Khah D, Ravichandran H, Anandasabapathy N, Orange DE, Spiera RF. 2025. Skin biopsies enhance prediction of clinical trajectory in diffuse cutaneous systemic sclerosis.. Arthritis Rheumatol.

Park J, De Gregorio R, Hissong E, Ozcelik E, Bartelo N, Dezem FSegato, Zhang L, Marção M, Chasteen H, Zheng Y et al.. 2025. The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs.. bioRxiv.

Foord C, Prjibelski AD, Hu W, Michielsen L, Vandelli A, Narykov O, Evans B, Hsu J, Belchikov N, Jarroux J et al.. 2025. A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.. Nat Commun. 16(1):8093.

Lv W, Zeng Y, Li C, Liang Y, Tao H, Zhu Y, Sui X, Li Y, Jiang S, Gao Q et al.. 2025. Spatial-Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment.. Cancer Discov. :OF1-OF22.

Khani F, Beg S, Park K, Kawaguchi K, Chiu Y-L, Robinson BD, Lis R, Stack EC, Scherr DS, Rosenberg JE et al.. 2025. SPINK1 immunohistochemistry: An ancillary tool to diagnose urothelial carcinoma in situ and urothelial dysplasia.. Pathol Res Pract. 273:156148.

Al-Thani NM, Zaghlool SB, Toor SM, Abou-Samra ABadi, Suhre K, Albagha OME. 2025. Subtyping of Type 2 Diabetes from a Large Middle Eastern Biobank: Implications for Precision Medicine.. Mol Metab. :102195.

Rubinelli L, Manzo OLaura, Sungho J, Del Gaudio I, Bareja R, Marino A, Palikhe S, Di Mauro V, Bucci M, Falcone DJ et al.. 2025. Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases.. Nat Commun. 16(1):1968.

Nuzzo PVitale, Rodrigues S, Ribeiro CFidalgo, Teixeira IFerrari, Fanelli GNicolo', Bleve S, Ravera F, Pakula H, Pederzoli F, Nanus DM et al.. 2025. Targeting Cancer Metabolism: Therapeutic Potential of the Fatty Acid Synthase (FASN) inhibitors.. Crit Rev Oncol Hematol. :104910.

Yost KE, Zhao Y, Hung KL, Zhu K, Xu D, M Corces R, Shams S, Louie BH, Sarmashghi S, Sundaram L et al.. 2025. Three-dimensional genome landscape of primary human cancers.. Nat Genet. 57(5):1189-1200.

Breves SL, Di Giammartino DCampigli, Nicholson J, Cirigliano S, Mahmood SRaza, Lee UJin, Martinez-Fundichely A, Jungverdorben J, Singhania R, Rajkumar S et al.. 2025. Three-dimensional regulatory hubs support oncogenic programs in glioblastoma.. Mol Cell.

Sternberg CN, Morgans AK. 2025. Treatment options in hormone-sensitive prostate cancer: targeting the androgen-sensitive pathway.. Future Oncol. 21(25):3227-3235.

Honigsberg R, Cruz T, Yoffe L, Tang MStephanie, Dicle O, Markowitz G, Michael M, Singh A, Altorki NK, Elemento O et al.. 2025. Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade.. bioRxiv.

Nath S, Claridge S, Granados GLara, Assaad MAl, Park E, Cavallo J-A, Nuwere U, Ackon MEsi, De Boni L, Baker S et al.. 2025. Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer.. Cell Rep Med. 6(7):102218.

Guevara D, Shin N, Boiko A, Valiev I, Elsaeed AG, Mosquera JMiguel, Assaad MAl, Manohar J, Sigouros M, Zaichikova A et al.. 2025. Unusual Presentation of Advanced Urothelial Cancer in a Young Patient.. Anticancer Res. 45(2):613-618.