Englander Institute for Precision Medicine

Publications

Found 931 results
Author Title Type [ Year(Asc)]
2026
Razzaq A, Anwardeen N, Naja K, Elashi AA, Thareja G, Diboun I, Suhre K, Elrayess MA.  2026.  Gene-Environment Interaction Mendelian Randomization Reveals Statin-Dependent Associations Between Metabolites and Lipid Traits.. Pharmaceuticals (Basel). 19(9)
Okur V, Marcus A, Falcone JN, Hurd MA, Stewart SL, Claudio K, Manohar J, Dealla F, Kumar S, Yeung M et al..  2026.  Genome sequencing identifies monogenic causes in adults with metabolic diseases.. J Endocr Soc. 10(7):bvag091.
Zhang X, Wong W, Cho HS, Yang D, Dixon G, Luo R, Liu D, Torre D, Umeda S, González F et al..  2026.  Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformation.. Dev Cell.
Stephan N, Halama A, Thareja G, Sarwath H, Grallert H, Peters A, Gieger C, Schmidt F, Graumann J, Suhre K.  2026.  Identification of Protein Signatures Reflecting Latent Variation in Aptamer-Based Affinity Proteomics.. J Proteome Res.
Uppal M, Bhinder B, Marderstein AR, Batlevi CLee, Falchi L, Hamlin P, Horwitz S, Kumar A, Noy A, Zelenetz AD et al..  2026.  Integrative Molecular Analysis Reveals Determinants of Clinical Outcomes in TP53-Mutated Diffuse Large B-Cell Lymphoma.. J Clin Oncol. :JCO2501928.
Ochoa-Cholán V, Miyauchi J, Ohara K, Kosaka T, Mohler JL, Mosquera JMiguel.  2026.  An International Survey Among Attending Urologists on the Term High-Grade Prostatic Intraepithelial Neoplasia: Advocating for Removal of 'High-Grade' From the Surgical Pathology Report.. Int J Urol. 33(6):e70530.
Abrahimi P, Khan JF, Duren-Lubanski A, Cai W, Marouf Y, Chen N, Hirschhorn D, Mammone R, Miranda IC, Tallman JE et al..  2026.  Intravesical mesothelin-based CAR T cells targeting MUC16 effectively control bladder cancer in preclinical models.. J Exp Med. 223(7)
Bleve S, Ravera F, Rodrigues S, Pederzoli F, Pakula H, Brighi N, Giunta EFrancesco, Schepisi G, Virga A, Gurioli G et al..  2026.  Lipidomic profiling in metastatic prostate cancer captures tumor metabolic rewiring and its modulation by androgen receptor-targeting therapy.. Prostate Cancer Prostatic Dis.
Solomon Z, Gomi R, Verzani Z, Wu A, Heras A, Permaul P, Balaji U, Gu J, Gomi K, Brown S et al..  2026.  Lower Nasal Sphingolipids in Pediatric Asthma and Cell-Type-Specific Effects of 17q21 Variants.. J Allergy Clin Immunol.
Chaudhry F, Kim TWan, Elemento O, Betel D.  2026.  Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's disease.. Front Aging Neurosci. 18:1730550.
Oro AE, Amagai M, Payne AS, Ellebrecht C, Hovnanian A, Anandasabapathy N, Leachman SA, Harris-Tryon T.  2026.  Mechanistic insights into emerging therapeutic platforms: The 72nd annual Montagna Symposium on the biology of skin.. J Invest Dermatol.
Anwardeen N, Razzaq A, Elashi AA, Thareja G, Diboun I, Naja K, Suhre K, Elrayess MA.  2026.  Metformin Treatment Potentially Modifies Genetically Driven Metabolite-HbA1c Associations: A Gene-Environment Interaction Mendelian Randomization Study.. Pharmaceuticals (Basel). 19(5)
Grimont A, Falvo DJ, Sisso WJ, Santos F, Chan CW, Zumbo P, Fall WB, Ferrick K, Pan G, Cleveland M et al..  2026.  Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis.. Dev Cell.
Likasitwatanakul P, Blinka SM, Zarka JG, Gebrael G, Weg E, Longoria O, Moore JA, Sharp A, de Bono J, Sternberg CN et al..  2026.  Molecular landscape of prostate cancers with clival metastases.. Oncologist. 31(4)
Toth R, Choi S, Le Naour-Vernet M, Schwanke F, Johnson JL, Tee EE, Yaron-Barir TM, Khochaba E, Derbyshire P, Colo A et al..  2026.  Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity.. Nat Plants. 12(2):465-480.
Koprulu M, Smith-Byrne K, Ferolito BRichard, Macdonald-Dunlop E, Luan J'an, Hedman ÅK, Ogamba CFranklin, Kuliesius J, Repetto L, Ramisch A et al..  2026.  Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome.. Cell. 189(11):3339-3357.e11.
Elemento O.  2026.  Multi-Hospital Electronic Health Record Foundation Models Without Data Sharing: A Comparison of Federated Learning and Inference-Time Ensembling.. medRxiv.
Surapaneni S, Kutler RB, Setzen SA, Kim YEun, Yao P, Siddiqui SH, Pitman MJ, Sulica L, Elemento O, Khosravi P et al..  2026.  A Multimodal Approach for Deep-Learning Classification of Vocal Fold Pathologies in Stroboscopy.. Laryngoscope.
Wolf A, Facciuto M, Damiecki M, Bramel ER, Park E, Young SE, Torres M, Nath S, Mazzaferro V, Schwartz M et al..  2026.  A novel preclinical platform to study FGFR2 fusion-driven cholangiocarcinoma☆.. JHEP Rep. :102090.
Xu C, Us I, Cohen-Setton J, Milo M, Sidders B, Fitzgibbon J, Melnick AM, Pan H, Bulusu KC, Elemento O.  2026.  PAIRWISE: Deep Learning-based Prediction of Effective Personalized Drug Combinations in Cancer.. Res Sq.
Kuo H-H, Bhinder B, Gokozan HN, Gorski K, Chandra P, Manohar J, Guevara D, Otilano J, Moyer J, Tranquille M et al..  2026.  Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities.. Sci Adv. 12(26):eadz3351.
Xing Y, Reznikov I, Ahmed ANur, Sidhu I, Wisnewski J, Farhat A, Prystupa A, Konieczny P, Mansfield K, Cooper ML et al..  2026.  Peripheral immune-inducer dendritic cells drive early-life allergic inflammation.. Nature.
Gao X, Garmezy B, Vuky J, Shen J, Sartor O, Sternberg CN, Dreicer R, Hussain M, Kalebasty ARezazadeh, Percent IJ et al..  2026.  Phase I/II Study of Bavdegalutamide, a Proteolysis-Targeting Chimera Androgen Receptor Degrader, in Metastatic Castration-Resistant Prostate Cancer.. J Clin Oncol. :JCO2502995.
De Boni L, Claridge S, Nath S, Tofani K, Stein BD, Park E, Steiner S, Elemento O, Pauli C, Hopkins BD.  2026.  Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors.. iScience. 29(3):114954.
Tignor NL, Koptyra M, Chowdhury S, Petralia F, Gritsenko MA, Ma W, Zhu Y, Marino GB, Song X, Migliozzi S et al..  2026.  Proteogenomic analysis of pediatric and AYA high-grade glioma reveals age-dependent biology, female-male differences, and kinase targets.. Cell Rep Med. :103024.