Englander Institute for Precision Medicine

Publications

Found 805 results
Author Title Type [ Year(Asc)]
2019
Danko DC, Meleshko D, Bezdan D, Mason C, Hajirasouliha I.  2019.  Minerva: an alignment- and reference-free approach to deconvolve Linked-Reads for metagenomics.. Genome Res. 29(1):116-124.
Gilvary C, Madhukar N, Elkhader J, Elemento O.  2019.  The Missing Pieces of Artificial Intelligence in Medicine.. Trends Pharmacol Sci. 40(8):555-564.
Do KTrinh, Rasp DJN-P, Kastenmüller G, Suhre K, Krumsiek J.  2019.  MoDentify: phenotype-driven module identification in metabolomics networks at different resolutions.. Bioinformatics. 35(3):532-534.
Kim S, Shah SB, Graney PL, Singh A.  2019.  Multiscale engineering of immune cells and lymphoid organs.. Nat Rev Mater. 4(6):355-378.
Puca L, Vlachostergios PJ, Beltran H.  2019.  Neuroendocrine Differentiation in Prostate Cancer: Emerging Biology, Models, and Therapies.. Cold Spring Harb Perspect Med. 9(2)
Ghandi M, Huang FW, Jané-Valbuena J, Kryukov GV, Lo CC, E McDonald R, Barretina J, Gelfand ET, Bielski CM, Li H et al..  2019.  Next-generation characterization of the Cancer Cell Line Encyclopedia.. Nature. 569(7757):503-508.
Berger A, Brady NJ, Bareja R, Robinson B, Conteduca V, Augello MA, Puca L, Ahmed A, Dardenne E, Lu X et al..  2019.  N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.. J Clin Invest. 129(9):3924-3940.
Zacharias HU, Altenbuchinger M, Schultheiss UT, Samol C, Kotsis F, Poguntke I, Sekula P, Krumsiek J, Köttgen A, Spang R et al..  2019.  A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease.. J Proteome Res. 18(4):1796-1805.
Springer NL, Iyengar NM, Bareja R, Verma A, Jochelson MS, Giri DD, Zhou XK, Elemento O, Dannenberg AJ, Fischbach C.  2019.  Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.. Am J Pathol. 189(10):2019-2035.
Karass M, Bareja R, Shelkey E, Vlachostergios PJ, Robinson BD, Khani F, Mosquera JMiguel, Scherr DS, Sboner A, Tagawa ST et al..  2019.  Oncogenic Addiction to ERBB2 Signaling Predicts Response to Trastuzumab in Urothelial Cancer.. J Natl Compr Canc Netw. 17(3):194-200.
Sivakumar R, Chan M, Shin JStella, Nishida-Aoki N, Kenerson HL, Elemento O, Beltran H, Yeung R, Gujral TS.  2019.  Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery.. Oncoimmunology. 8(12):e1670019.
Liu B, Li L, Yang G, Geng C, Luo Y, Wu W, Manyam GC, Korentzelos D, Park S, Tang Z et al..  2019.  PARP Inhibition Suppresses GR-MYCN-CDK5-RB1-E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer.. Clin Cancer Res. 25(22):6839-6851.
Beltran H, Oromendia C, Danila DC, Montgomery B, Hoimes C, Szmulewitz RZ, Vaishampayan U, Armstrong AJ, Stein M, Pinski J et al..  2019.  A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers.. Clin Cancer Res. 25(1):43-51.
Malikic S, Mehrabadi FRashidi, Ciccolella S, Rahman MKhaledur, Ricketts C, Haghshenas E, Seidman D, Hach F, Hajirasouliha I, S Sahinalp C.  2019.  PhISCS: a combinatorial approach for subperfect tumor phylogeny reconstruction via integrative use of single-cell and bulk sequencing data.. Genome Res. 29(11):1860-1877.
Jayaram A, Wingate A, Wetterskog D, Conteduca V, Khalaf D, Sharabiani MTaghavi Az, Calabrò F, Barwell L, Feyerabend S, Grande E et al..  2019.  Plasma Androgen Receptor Copy Number Status at Emergence of Metastatic Castration-Resistant Prostate Cancer: A Pooled Multicohort Analysis.. JCO Precis Oncol. 3
Prandi D, Demichelis F.  2019.  Ploidy- and Purity-Adjusted Allele-Specific DNA Analysis Using CLONETv2.. Curr Protoc Bioinformatics. 67(1):e81.
Lue JK, Prabhu SA, Liu Y, Gonzalez Y, Verma A, Mundi PS, Abshiru N, Camarillo JM, Mehta S, Chen EI et al..  2019.  Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.. Clin Cancer Res. 25(17):5271-5283.
Boehm KMichael, Bhinder B, Raja VJoseph, Dephoure N, Elemento O.  2019.  Predicting peptide presentation by major histocompatibility complex class I: an improved machine learning approach to the immunopeptidome.. BMC Bioinformatics. 20(1):7.
Subbaramaiah K, Iyengar NM, Morrow M, Elemento O, Zhou XKathy, Dannenberg AJ.  2019.  Prostaglandin E down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.. J Biol Chem. 294(1):361-371.
Persi E, Prandi D, Wolf YI, Pozniak Y, Barnabas GD, Levanon K, Barshack I, Barbieri C, Gasperini P, Beltran H et al..  2019.  Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues.. Proc Natl Acad Sci U S A. 116(34):16987-16996.
Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, G Han C, Coleman I et al..  2019.  Publisher Correction: The long tail of oncogenic drivers in prostate cancer.. Nat Genet. 51(7):1194.
Lhuillier C, Rudqvist N-P, Elemento O, Formenti SC, Demaria S.  2019.  Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system.. Genome Med. 11(1):40.
Fradet Y, Bellmunt J, Vaughn DJ, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A et al..  2019.  Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up.. Ann Oncol. 30(6):970-976.
Rodrigues DNava, Casiraghi N, Romanel A, Crespo M, Miranda S, Rescigno P, Figueiredo I, Riisnaes R, Carreira S, Sumanasuriya S et al..  2019.  RB1 Heterogeneity in Advanced Metastatic Castration-Resistant Prostate Cancer.. Clin Cancer Res. 25(2):687-697.
Roos-Weil D, Decaudin C, Armand M, Della-Valle V, Diop M'boybaK, Ghamlouch H, Ropars V, Hérate C, Lara D, Durot E et al..  2019.  A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.. Cancer Discov. 9(6):796-811.