Englander Institute for Precision Medicine

Publications

Found 790 results
Author Title Type [ Year(Asc)]
2021
Karkampouna S, La Manna F, Benjak A, Kiener M, De Menna M, Zoni E, Grosjean J, Klima I, Garofoli A, Bolis M et al..  2021.  Patient-derived xenografts and organoids model therapy response in prostate cancer.. Nat Commun. 12(1):1117.
Jayaram A, Wingate A, Wetterskog D, Wheeler G, Sternberg CN, Jones R, Berruti A, Lefresne F, Lahaye M, Thomas S et al..  2021.  Plasma tumor gene conversions after one cycle abiraterone acetate for metastatic castration-resistant prostate cancer: a biomarker analysis of a multicenter international trial.. Ann Oncol. 32(6):726-735.
Clement CC, Nanaware PP, Yamazaki T, Negroni MPia, Ramesh K, Morozova K, Thangaswamy S, Graves A, Kim HJung, Li TWanxia et al..  2021.  Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery.. Immunity. 54(4):721-736.e10.
Marderstein AR, Kulm S, Peng C, Tamimi R, Clark AG, Elemento O.  2021.  A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk.. Am J Hum Genet. 108(9):1752-1764.
Buqué A, Bloy N, Kroemer G, Galluzzi L.  2021.  Possible mechanisms of cancer prevention by nicotinamide.. Br J Pharmacol. 178(10):2034-2040.
Gillessen S, Sauvé N, Collette L, Daugaard G, de Wit R, Albany C, Tryakin A, Fizazi K, Stahl O, Gietema JA et al..  2021.  Predicting Outcomes in Men With Metastatic Nonseminomatous Germ Cell Tumors (NSGCT): Results From the IGCCCG Update Consortium.. J Clin Oncol. 39(14):1563-1574.
Kolin DA, Kulm S, Elemento O.  2021.  Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank.. Sci Rep. 11(1):21340.
Rendeiro AF, Casano J, Vorkas CKyriakos, Singh H, Morales A, DeSimone RA, Ellsworth GB, Soave R, Kapadia SN, Saito K et al..  2021.  Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression.. Life Sci Alliance. 4(2)
Clement CC, Nanaware PP, Stern LJ, Santambrogio L.  2021.  A protocol for qualitative and quantitative measurement of endosomal processing using hot spot analysis.. STAR Protoc. 2(3):100648.
Dixon G, Pan H, Yang D, Rosen BP, Jashari T, Verma N, Pulecio J, Caspi I, Lee K, Stransky S et al..  2021.  QSER1 protects DNA methylation valleys from de novo methylation.. Science. 372(6538)
Petroni G, Buqué A, Yamazaki T, Bloy N, Di Liberto M, Chen-Kiang S, Formenti SC, Galluzzi L.  2021.  Radiotherapy Delivered before CDK4/6 Inhibitors Mediates Superior Therapeutic Effects in ER Breast Cancer.. Clin Cancer Res. 27(7):1855-1863.
Lhuillier C, Rudqvist N-P, Yamazaki T, Zhang T, Charpentier M, Galluzzi L, Dephoure N, Clement CC, Santambrogio L, Zhou XKathy et al..  2021.  Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control.. J Clin Invest. 131(5)
Grbesa I, Augello MA, Liu D, McNally DR, Gaffney CD, Huang D, Lin K, Ivenitsky D, Goueli R, Robinson BD et al..  2021.  Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.. Cell Rep. 36(10):109625.
Loehr A, Patnaik A, Campbell D, Shapiro J, Bryce AH, McDermott R, Sautois B, Vogelzang NJ, Bambury RM, Voog E et al..  2021.  Response to Rucaparib in BRCA-Mutant Metastatic Castration-Resistant Prostate Cancer Identified by Genomic Testing in the TRITON2 Study.. Clin Cancer Res. 27(24):6677-6686.
Kassambara A, Herviou L, Ovejero S, Jourdan M, Thibaut C, Vikova V, Pasero P, Elemento O, Moreaux J.  2021.  RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.. Leukemia. 35(5):1451-1462.
Alaterre E, Vikova V, Kassambara A, Bruyer A, Robert N, Requirand G, Bret C, Herbaux C, Vincent L, Cartron G et al..  2021.  RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma.. J Pers Med. 11(10)
Elemento O.  2021.  The road from Rous sarcoma virus to precision medicine.. J Exp Med. 218(4)
Marciscano AE, Anandasabapathy N.  2021.  The role of dendritic cells in cancer and anti-tumor immunity.. Semin Immunol. 52:101481.
E Weissler H, Naumann T, Andersson T, Ranganath R, Elemento O, Luo Y, Freitag DF, Benoit J, Hughes MC, Khan F et al..  2021.  The role of machine learning in clinical research: transforming the future of evidence generation.. Trials. 22(1):537.
Merseburger AS, Castellano D, Powles T, Loriot Y, Retz M, Voortman J, Huddart RA, Gedye C, van der Heijden MS, Gurney H et al..  2021.  Safety and Efficacy of Atezolizumab in Understudied Populations with Pretreated Urinary Tract Carcinoma: Subgroup Analyses of the SAUL Study in Real-World Practice.. J Urol. 206(2):240-251.
Bamias A, Merseburger AS, Loriot Y, James N, Choy E, Castellano D, Lopez-Rios F, Calabrò F, Kramer M, de Velasco G et al..  2021.  SAUL, a single-arm study of atezolizumab for chemotherapy-pretreated locally advanced or metastatic carcinoma of the urinary tract: outcomes by key baseline factors, PD-L1 expression and prior platinum therapy.. ESMO Open. 6(3):100152.
Niiranen L, Mäkelä KA, Dona A, Krumsiek J, Karhu T, Mäkinen MJ, Thalmann O, Saarela S, Herzig K-H.  2021.  Seasonal Regulation of Metabolism: The Effect of Wintertime Fasting and Autumnal Fattening on Key Central Regulators of Metabolism and the Metabolic Profile of the Raccoon Dog ().. Int J Mol Sci. 22(9)
Butler D, Mozsary C, Meydan C, Foox J, Rosiene J, Shaiber A, Danko D, Afshinnekoo E, MacKay M, Sedlazeck FJ et al..  2021.  Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions.. Nat Commun. 12(1):1660.
Rivas MA, Meydan C, Chin CR, Challman MF, Kim D, Bhinder B, Kloetgen A, Viny AD, Teater MR, McNally DR et al..  2021.  Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.. Nat Immunol. 22(2):240-253.
Rendeiro AF, Ravichandran H, Bram Y, Chandar V, Kim J, Meydan C, Park J, Foox J, Hether T, Warren S et al..  2021.  The spatial landscape of lung pathology during COVID-19 progression.. Nature. 593(7860):564-569.