Englander Institute for Precision Medicine

Publications

Found 840 results
Author Title Type [ Year(Asc)]
2021
Beg S, Bareja R, Ohara K, Eng KWha, Wilkes DC, Pisapia DJ, Zoughbi WAl, Kudman S, Zhang W, Rao R et al..  2021.  Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.. Transl Oncol. 14(1):100944.
Vitale I, Shema E, Loi S, Galluzzi L.  2021.  Intratumoral heterogeneity in cancer progression and response to immunotherapy.. Nat Med. 27(2):212-224.
Sweeney C, Bracarda S, Sternberg CN, Chi KN, Olmos D, Sandhu S, Massard C, Matsubara N, Alekseev B, Parnis F et al..  2021.  Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial.. Lancet. 398(10295):131-142.
Buqué A, Galluzzi L, Kroemer G.  2021.  Ketosis versus carbotoxicity - metabolism determines the outcome of cancer immunotherapy.. Mol Cell Oncol. 8(1):1868266.
Marderstein AR, Davenport ER, Kulm S, Van Hout CV, Elemento O, Clark AG.  2021.  Leveraging phenotypic variability to identify genetic interactions in human phenotypes.. Am J Hum Genet. 108(1):49-67.
Kaya C, Dorsaint P, Mercurio S, Campbell AM, Eng KWha, Nikiforova MN, Elemento O, Nikiforov YE, Sboner A.  2021.  Limitations of Detecting Genetic Variants from the RNA Sequencing Data in Tissue and Fine-Needle Aspiration Samples.. Thyroid. 31(4):589-595.
Sheffield NC, Stolarczyk M, Reuter VP, Rendeiro AF.  2021.  Linking big biomedical datasets to modular analysis with Portable Encapsulated Projects.. Gigascience. 10(12)
Yamazaki T, Wennerberg E, Hensler M, Buqué A, Kraynak J, Fucikova J, Zhou XKathy, Sveinbjørnsson B, Rekdal Ø, Demaria S et al..  2021.  LTX-315-enabled, radiotherapy-boosted immunotherapeutic control of breast cancer by NK cells.. Oncoimmunology. 10(1):1962592.
Rendeiro AF, Vorkas CKyriakos, Krumsiek J, Singh HK, Kapadia SN, Cappelli LVincenzo, Cacciapuoti MTeresa, Inghirami G, Elemento O, Salvatore M.  2021.  Metabolic and Immune Markers for Precise Monitoring of COVID-19 Severity and Treatment.. Front Immunol. 12:809937.
Zacharias HU, Hertel J, Johar H, Pietzner M, Lukaschek K, Atasoy S, Kunze S, Völzke H, Nauck M, Friedrich N et al..  2021.  A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression.. Mol Psychiatry. 26(12):7372-7383.
Li J, Duran MA, Dhanota N, Chatila WK, Bettigole SE, Kwon J, Sriram RK, Humphries MP, Salto-Tellez M, James JA et al..  2021.  Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.. Cancer Discov. 11(5):1212-1227.
Naidoo M, Levine F, Gillot T, Orunmuyi AT, E Olapade-Olaopa O, Ali T, Krampis K, Pan C, Dorsaint P, Sboner A et al..  2021.  MicroRNA-1205 Regulation of FRYL in Prostate Cancer.. Front Cell Dev Biol. 9:647485.
Armstrong AJ, Li X, Tucker M, Li S, Mu XJasmine, Eng KWha, Sboner A, Rubin M, Gerstein M.  2021.  Molecular medicine tumor board: whole-genome sequencing to inform on personalized medicine for a man with advanced prostate cancer.. Prostate Cancer Prostatic Dis. 24(3):786-793.
Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I, Rendeiro AF, Amin ADipak, Schapiro D et al..  2021.  A molecular single-cell lung atlas of lethal COVID-19.. Nature. 595(7865):114-119.
Buqué A, Perez-Lanzón M, Petroni G, Humeau J, Bloy N, Yamazaki T, Sato A, Kroemer G, Galluzzi L.  2021.  MPA/DMBA-driven mammary carcinomas.. Methods Cell Biol. 163:1-19.
Wörheide MA, Krumsiek J, Kastenmüller G, Arnold M.  2021.  Multi-omics integration in biomedical research - A metabolomics-centric review.. Anal Chim Acta. 1141:144-162.
Bloehdorn J, Braun A, Taylor-Weiner A, Jebaraj BMichael Ch, Robrecht S, Krzykalla J, Pan H, Giza A, Akylzhanova G, Holzmann K et al..  2021.  Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.. Nat Commun. 12(1):5395.
Persi E, Wolf YI, Horn D, Ruppin E, Demichelis F, Gatenby RA, Gillies RJ, Koonin EV.  2021.  Mutation-selection balance and compensatory mechanisms in tumour evolution.. Nat Rev Genet. 22(4):251-262.
Morciano G, Pedriali G, Bonora M, Pavasini R, Mikus E, Calvi S, Bovolenta M, Lebiedzinska-Arciszewska M, Pinotti M, Albertini A et al..  2021.  A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients.. Cell Rep. 35(2):108983.
Nilsson-Payant BE, Uhl S, Grimont A, Doane AS, Cohen P, Patel RS, Higgins CA, Acklin JA, Bram Y, Chandar V et al..  2021.  The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication.. J Virol. 95(23):e0125721.
Doane AS, Chu C-S, Di Giammartino DCampigli, Rivas MA, Hellmuth JC, Jiang Y, Yusufova N, Alonso A, Roeder RG, Apostolou E et al..  2021.  OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity.. Nat Immunol. 22(10):1327-1340.
M Calvo-Vidal N, Zamponi N, Krumsiek J, Stockslager MA, Revuelta MV, Phillip JM, Marullo R, Tikhonova E, Kotlov N, Patel J et al..  2021.  Oncogenic HSP90 Facilitates Metabolic Alterations in Aggressive B-cell Lymphomas.. Cancer Res. 81(20):5202-5216.
Che M, Chaturvedi A, Munro SA, Pitzen SP, Ling A, Zhang W, Mentzer J, Ku S-Y, Puca L, Zhu Y et al..  2021.  Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer.. Nat Commun. 12(1):6377.
Shah Y, Verma A, Marderstein AR, White J, Bhinder B, J Medina SGarcia, Elemento O.  2021.  Pan-cancer analysis reveals molecular patterns associated with age.. Cell Rep. 37(10):110100.
Thorand B, Zierer A, Buyukozkan M, Krumsiek J, Bauer A, Schederecker F, Sudduth-Klinger J, Meisinger C, Grallert H, Rathmann W et al..  2021.  A Panel of 6 Biomarkers Significantly Improves the Prediction of Type 2 Diabetes in the MONICA/KORA Study Population.. J Clin Endocrinol Metab. 106(4):e1647-e1659.